Gene Symbol | SLC16A10 |
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Entrez Gene | 117247 |
Alt Symbol | MCT10, PRO0813, TAT1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 16 (aromatic amino acid transporter), member 10 |
Other Description | MCT 10|T-type amino acid transporter 1|aromatic amino acid transporter 1|monocarboxylate transporter 10|solute carrier family 16 (monocarboxylic acid transporters), member 10|solute carrier family 16 member 10|solute carrier family 16, member 10 (aromatic amino acid transporter) |
Swissprots | Q8TF71 B3KWY0 Q8WVI5 Q6ZMG0 |
Accessions | EAW48298 EAW48299 Q8TF71 AB057445 BAB84670 AF116652 AAF71072 AK126183 BAG54292 AK172789 BAD18768 BC017968 AAH17968 BC034031 AAH34031 BC066985 AAH66985 XM_005266818 XP_005266875 XM_005266819 XP_005266876 XM_006715329 XP_006715392 XM_011535422 XP_011533724 XM_011535423 XP_011533725 NM_018593 NP_061063 |
Function | Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Basolateral cell membrane {ECO:0000250}. |
Tissue Specificity | Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart. {ECO:0000269|PubMed:11827462}. |
Top Pathways | Protein digestion and absorption |
TAT1 CRISPR/Cas9 KO Plasmid (h) - sc-414111 from Santa Cruz Biotechnology
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TAT1 HDR Plasmid (h) - sc-414111-HDR from Santa Cruz Biotechnology
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TAT1 Double Nickase Plasmid (h) - sc-414111-NIC from Santa Cruz Biotechnology
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TAT1 Double Nickase Plasmid (h2) - sc-414111-NIC-2 from Santa Cruz Biotechnology
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TAT1 CRISPR Activation Plasmid (h) - sc-414111-ACT from Santa Cruz Biotechnology
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TAT1 CRISPR Activation Plasmid (h2) - sc-414111-ACT-2 from Santa Cruz Biotechnology
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TAT1 Lentiviral Activation Particles (h) - sc-414111-LAC from Santa Cruz Biotechnology
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TAT1 Lentiviral Activation Particles (h2) - sc-414111-LAC-2 from Santa Cruz Biotechnology
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TAT1 siRNA (h) - sc-95192 from Santa Cruz Biotechnology
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TAT1 shRNA Plasmid (h) - sc-95192-SH from Santa Cruz Biotechnology
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TAT1 shRNA (h) Lentiviral Particles - sc-95192-V from Santa Cruz Biotechnology
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SLC16A10 RNAi - H00117247-R01 from Novus Biologicals
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MISSION® esiRNA - EHU057211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19423 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19423 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06326 from Sigma-Aldrich
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SLC16A10 siRNA (Human) - CRJ4564 from Cohesion Biosciences
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SLC16A10 - MBS8221690 from MyBioSource
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shRNA set against Human SLC16A10 (NM_018593.4) - SHH408564 from Creative biogene
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Human SLC16A10 siRNA - orb275065 from Biorbyt
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SLC16A10 shRNA Plasmid (Human) - CHJ4564 from Cohesion Biosciences
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SLC16A10 miRNA 3'UTR clone - MiUTR3H-09303 from Creative biogene
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