Gene Symbol | CCS |
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Entrez Gene | 9973 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | copper chaperone for superoxide dismutase |
Other Description | superoxide dismutase copper chaperone |
Swissprots | Q8NEV0 O14618 Q2M366 |
Accessions | EAW74549 EAW74550 EAW74551 O14618 AF002210 AAC51764 AY113179 AAM50090 BC105016 AAI05017 BC112055 AAI12056 CR541928 CAG46726 XR_247219 NM_005125 NP_005116 |
Function | Delivers copper to copper zinc superoxide dismutase (SOD1). |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9726962}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Amyotrophic lateral sclerosis (ALS) |
CCS CRISPR/Cas9 KO Plasmid (h) - sc-402130 from Santa Cruz Biotechnology
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CCS HDR Plasmid (h) - sc-402130-HDR from Santa Cruz Biotechnology
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CCS Double Nickase Plasmid (h) - sc-402130-NIC from Santa Cruz Biotechnology
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CCS Double Nickase Plasmid (h2) - sc-402130-NIC-2 from Santa Cruz Biotechnology
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CCS CRISPR Activation Plasmid (h) - sc-402130-ACT from Santa Cruz Biotechnology
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CCS CRISPR Activation Plasmid (h2) - sc-402130-ACT-2 from Santa Cruz Biotechnology
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CCS Lentiviral Activation Particles (h) - sc-402130-LAC from Santa Cruz Biotechnology
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CCS Lentiviral Activation Particles (h2) - sc-402130-LAC-2 from Santa Cruz Biotechnology
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CCS siRNA (h) - sc-29956 from Santa Cruz Biotechnology
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CCS shRNA Plasmid (h) - sc-29956-SH from Santa Cruz Biotechnology
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CCS shRNA (h) Lentiviral Particles - sc-29956-V from Santa Cruz Biotechnology
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CCS/SOD4 RNAi - H00009973-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5664 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5664 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00851 from Sigma-Aldrich
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CCS siRNA (Human) - CRH6710 from Cohesion Biosciences
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CCS - MBS8222106 from MyBioSource
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shRNA set against Human CCS (NM_005125.1) - SHH258281 from Creative biogene
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shRNA set against Human CCS(NM_005125.1) - SHG153943 from Creative biogene
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CCS shRNA Plasmid (Human) - CHH6710 from Cohesion Biosciences
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CCS miRNA 3'UTR clone - MiUTR1H-01832 from Creative biogene
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