Gene Symbol | FBXW4 |
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Entrez Gene | 6468 |
Alt Symbol | DAC, FBW4, FBWD4, SHFM3, SHSF3 |
Species | Human |
Gene Type | protein-coding |
Description | F-box and WD repeat domain containing 4 |
Other Description | F-box and WD-40 domain protein 4|F-box and WD-40 domain-containing protein 4|F-box/WD repeat protein 4|F-box/WD repeat-containing protein 4|dactylin |
Swissprots | Q96IM6 P57775 Q5SVS1 |
Accessions | EAW49751 EAW49752 EAW49753 P57775 AF281859 AAG22739 AK056917 AK123173 AK314735 BAG37276 BC007380 AAH07380 BC063415 AAH63415 XM_005270053 XP_005270110 XR_246102 NM_022039 NP_071322 |
Function | Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. |
Tissue Specificity | Expressed in brain, kidney, lung and liver. |
SHFM3 CRISPR/Cas9 KO Plasmid (h) - sc-411004 from Santa Cruz Biotechnology
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SHFM3 HDR Plasmid (h) - sc-411004-HDR from Santa Cruz Biotechnology
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SHFM3 Double Nickase Plasmid (h) - sc-411004-NIC from Santa Cruz Biotechnology
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SHFM3 Double Nickase Plasmid (h2) - sc-411004-NIC-2 from Santa Cruz Biotechnology
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SHFM3 CRISPR Activation Plasmid (h) - sc-411004-ACT from Santa Cruz Biotechnology
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SHFM3 CRISPR Activation Plasmid (h2) - sc-411004-ACT-2 from Santa Cruz Biotechnology
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SHFM3 Lentiviral Activation Particles (h) - sc-411004-LAC from Santa Cruz Biotechnology
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SHFM3 Lentiviral Activation Particles (h2) - sc-411004-LAC-2 from Santa Cruz Biotechnology
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SHFM3 siRNA (h) - sc-90449 from Santa Cruz Biotechnology
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SHFM3 shRNA Plasmid (h) - sc-90449-SH from Santa Cruz Biotechnology
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SHFM3 shRNA (h) Lentiviral Particles - sc-90449-V from Santa Cruz Biotechnology
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SHFM3 RNAi - H00006468-R01 from Novus Biologicals
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MISSION® esiRNA - EHU104611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8574 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8574 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05342 from Sigma-Aldrich
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FBXW4 siRNA (Human) - CRH4371 from Cohesion Biosciences
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FBXW4 - MBS8225004 from MyBioSource
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shRNA set against Human FBXW4 (NM_022039.3) - SHH293545 from Creative biogene
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shRNA set against Human FBXW4(NM_022039.3) - SHH053695 from Creative biogene
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FBXW4 shRNA Plasmid (Human) - CHH4371 from Cohesion Biosciences
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FBXW4 miRNA 3'UTR clone - MiUTR1H-03576 from Creative biogene
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