Gene Symbol | CAPG |
---|---|
Entrez Gene | 822 |
Alt Symbol | AFCP, HEL-S-66, MCP |
Species | Human |
Gene Type | protein-coding |
Description | capping protein (actin filament), gelsolin-like |
Other Description | actin regulatory protein CAP-G|actin-regulatory protein CAP-G|epididymis secretory protein Li 66|gelsolin-like capping protein|macrophage capping protein|macrophage-capping protein |
Swissprots | D6W5K8 B8ZZS7 Q53SA7 P40121 |
Accessions | AAA92670 AAY24128 EAW99517 EAW99518 EAW99519 EAW99520 P40121 AK130130 AK225374 AK225378 AK300507 BAG62220 AK309290 AK313898 BAG36621 AU099216 BC000728 AAH00728 BC014549 AAH14549 BU626913 DQ892163 ABM83089 DQ895357 ABM86283 FJ224312 ACI46004 M94345 AAA59570 XM_005264581 XP_005264638 XM_011533122 XP_011531424 XM_011533123 XP_011531425 NM_001256139 NP_001243068 NM_001256140 NP_001243069 NM_001747 NP_001738 |
Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Macrophages and macrophage-like cells. |
CapG CRISPR/Cas9 KO Plasmid (h) - sc-416526 from Santa Cruz Biotechnology
|
||||||||
CapG HDR Plasmid (h) - sc-416526-HDR from Santa Cruz Biotechnology
|
||||||||
CapG Double Nickase Plasmid (h) - sc-416526-NIC from Santa Cruz Biotechnology
|
||||||||
CapG Double Nickase Plasmid (h2) - sc-416526-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CapG CRISPR Activation Plasmid (h) - sc-416526-ACT from Santa Cruz Biotechnology
|
||||||||
CapG CRISPR Activation Plasmid (h2) - sc-416526-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CapG Lentiviral Activation Particles (h) - sc-416526-LAC from Santa Cruz Biotechnology
|
||||||||
CapG Lentiviral Activation Particles (h2) - sc-416526-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CapG siRNA (h) - sc-44920 from Santa Cruz Biotechnology
|
||||||||
CapG shRNA Plasmid (h) - sc-44920-SH from Santa Cruz Biotechnology
|
||||||||
CapG shRNA (h) Lentiviral Particles - sc-44920-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU129321 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5337 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5337 from Sigma-Aldrich
|
||||||||
CAPG siRNA (Human) - CRH0576 from Cohesion Biosciences
|
||||||||
CAPG - MBS8217535 from MyBioSource
|
||||||||
shRNA set against Human CAPG (NM_001747.3) - SHH254257 from Creative biogene
|
||||||||
Human CAPG siRNA - orb261078 from Biorbyt
|
||||||||
CAPG shRNA Plasmid (Human) - CHH0576 from Cohesion Biosciences
|
||||||||
CAPG miRNA 3'UTR clone - MiUTR3H-01364 from Creative biogene
|