| Gene Symbol | GALNT7 |
|---|---|
| Entrez Gene | 51809 |
| Alt Symbol | GALNAC-T7, GalNAcT7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | polypeptide N-acetylgalactosaminyltransferase 7 |
| Other Description | N-acetylgalactosaminyltransferase 7|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)|polypeptide GalNAc transferase 7|pp-GaNTase 7|protein-UDP acetylgalactosaminyltransferase 7 |
| Swissprots | Q86SF2 Q7Z5W7 B3KQU3 Q9UJ28 |
| Accessions | AAY41020 CAI72154 EAX04761 Q86SF2 AJ002744 CAB60270 AJ505958 CAD44538 AK128437 AK295509 BAG58426 BC020541 BC035303 AAH35303 BC046129 AAH46129 BC047468 AAH47468 DB238519 JF432835 ADZ16052 XM_005263062 XP_005263119 XM_011532025 XP_011530327 NM_017423 NP_059119 |
| Function | Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Tissue Specificity | Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS. {ECO:0000269|PubMed:10544240}. |
| Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T7 CRISPR/Cas9 KO Plasmid (h) - sc-412248 from Santa Cruz Biotechnology
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GalNAc-T7 HDR Plasmid (h) - sc-412248-HDR from Santa Cruz Biotechnology
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GalNAc-T7 Double Nickase Plasmid (h) - sc-412248-NIC from Santa Cruz Biotechnology
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GalNAc-T7 Double Nickase Plasmid (h2) - sc-412248-NIC-2 from Santa Cruz Biotechnology
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GalNAc-T7 CRISPR Activation Plasmid (h) - sc-412248-ACT from Santa Cruz Biotechnology
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GalNAc-T7 CRISPR Activation Plasmid (h2) - sc-412248-ACT-2 from Santa Cruz Biotechnology
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GalNAc-T7 Lentiviral Activation Particles (h) - sc-412248-LAC from Santa Cruz Biotechnology
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GalNAc-T7 Lentiviral Activation Particles (h2) - sc-412248-LAC-2 from Santa Cruz Biotechnology
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GalNAc-T7 siRNA (h) - sc-62364 from Santa Cruz Biotechnology
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GalNAc-T7 shRNA Plasmid (h) - sc-62364-SH from Santa Cruz Biotechnology
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GalNAc-T7 shRNA (h) Lentiviral Particles - sc-62364-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU005951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9112 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9112 from Sigma-Aldrich
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GALNT7 siRNA (Human) - CRH9954 from Cohesion Biosciences
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GALNT7 - MBS8212165 from MyBioSource
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shRNA set against Human GALNT7 (NM_017423.2) - SHH299085 from Creative biogene
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shRNA set against Human GALNT7(NM_017423.2) - SHH076439 from Creative biogene
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GALNT7 shRNA Plasmid (Human) - CHH9954 from Cohesion Biosciences
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GALNT7 miRNA 3'UTR clone - MiUTR1H-03942 from Creative biogene
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