| Gene Symbol |
CEP250
|
| Entrez Gene |
11190
|
| Alt Symbol |
C-NAP1, CEP2, CNAP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centrosomal protein 250kDa
|
| Other Description |
250 kDa centrosomal protein|centrosomal Nek2-associated protein 1|centrosomal protein, 250-KD|centrosome associated protein|centrosome-associated protein CEP250
|
| Swissprots |
O60588 O14812 Q9BV73 Q9H450 E1P5Q3
|
| Accessions |
CAB89415 CAI42839 CAI42840 CAO03345 CAO03346 EAW76204 EAW76205 EAW76206 EAW76207 Q9BV73 AB621828 BAK64163 AF022655 AAC06349 AF049105 AAC07988 AK297572 BAG59963 AK307861 AL037087 BC001433 BC071869 AAH71869 BC144706 BC172439 AAI72439 BM996444 XM_005260262 XP_005260319 XM_005260263 XP_005260320 XM_005260264 XP_005260321 XM_005260265 XP_005260322 XM_006723690 XP_006723753 XM_006723691 XP_006723754 XM_006723692 XP_006723755 XM_006723693 XP_006723756 XM_006723694 XP_006723757 XM_006723695 XP_006723758 XM_011528517 XP_011526819 XM_011528518 XP_011526820 XM_011528519 XP_011526821 XM_011528520 XP_011526822 NM_007186 NP_009117 NM_001035518
|
| Function |
Probably plays an important role in centrosome cohesion during interphase.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:9647649}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:9647649}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:9647649}. Note=Component of the core centrosome. In interphase cells, it specifically associates with the proximal ends of both mother and daughter centrioles. Associates with the centrosome in interphase cells. In mitotic cells, it dissociates from the mitotic spindle poles. At the end of cell division, it reaccumulates at centrosomes. In photoreceptors, found at the proximal ends of basal bodies.
|
| Tissue Specificity |
Ubiquitously and weakly expressed.
|