Gene Symbol | SZT2 |
---|---|
Entrez Gene | 23334 |
Alt Symbol | C1orf84, EIEE18, KIAA0467, SZT2A, SZT2B |
Species | Human |
Gene Type | protein-coding |
Description | seizure threshold 2 homolog (mouse) |
Other Description | RP11-506B15.1|protein SZT2|seizure threshold 2 protein homolog |
Swissprots | Q5T012 Q9UFQ8 Q5XKC7 A7E2X4 Q5T011 Q6ZT24 A0PJK5 O75055 Q7Z636 Q6ZNI8 Q8NAY9 Q5JUY7 Q9H5H7 |
Accessions | CCQ43499 EAX07095 EAX07096 EAX07097 EAX07098 Q5T011 AB007936 BAA32312 AK001249 AK027078 BAB15649 AK091821 BAC03755 AK126972 BAC86771 AK131107 BAC85157 AL117402 CAB55903 BC017576 AAH17576 BC041069 AAH41069 BC051343 BC052802 AAH52802 BC082968 AAH82968 BC151232 AAI51233 BF826848 BF926328 BF927604 BU101724 BU633294 BX423490 DY655545 HG491959 XM_005270686 XP_005270743 XM_006710501 XP_006710564 XM_011541103 XP_011539405 XM_011541104 XP_011539406 XM_011541105 XP_011539407 XM_011541106 XP_011539408 XM_011541107 XP_011539409 NM_015284 NP_056099 NM_001012960 NM_001012961 NM_182518 |
Function | Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold (By similarity). {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Tissue Specificity | Expressed in the brain, predominantly in the parietal and frontal cortex, as well as in dorsal root ganglia. Expressed in peripheral white blood cells. {ECO:0000269|PubMed:20045724, ECO:0000269|PubMed:23932106}. |
SZT2 CRISPR/Cas9 KO Plasmid (h) - sc-411718 from Santa Cruz Biotechnology
|
||||||||
SZT2 HDR Plasmid (h) - sc-411718-HDR from Santa Cruz Biotechnology
|
||||||||
SZT2 Double Nickase Plasmid (h) - sc-411718-NIC from Santa Cruz Biotechnology
|
||||||||
SZT2 Double Nickase Plasmid (h2) - sc-411718-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SZT2 CRISPR Activation Plasmid (h) - sc-411718-ACT from Santa Cruz Biotechnology
|
||||||||
SZT2 CRISPR Activation Plasmid (h2) - sc-411718-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SZT2 Lentiviral Activation Particles (h) - sc-411718-LAC from Santa Cruz Biotechnology
|
||||||||
SZT2 Lentiviral Activation Particles (h2) - sc-411718-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SZT2 siRNA (h) - sc-78949 from Santa Cruz Biotechnology
|
||||||||
SZT2 shRNA Plasmid (h) - sc-78949-SH from Santa Cruz Biotechnology
|
||||||||
SZT2 shRNA (h) Lentiviral Particles - sc-78949-V from Santa Cruz Biotechnology
|
||||||||
SZT2 RNAi - H00023334-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU118781 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN11079 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11079 from Sigma-Aldrich
|
||||||||
SZT2 siRNA (Human) - CRH8189 from Cohesion Biosciences
|
||||||||
SZT2 - MBS8229563 from MyBioSource
|
||||||||
shRNA set against Human Szt2 (NM_015284.3) - SHH422188 from Creative biogene
|
||||||||
Human SZT2 siRNA - orb268691 from Biorbyt
|
||||||||
SZT2 shRNA Plasmid (Human) - CHH8189 from Cohesion Biosciences
|
||||||||
SZT2 miRNA 3'UTR clone - MiUTR4H-TG04774 from Creative biogene
|