Gene Symbol | PSAT1 |
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Entrez Gene | 29968 |
Alt Symbol | EPIP, NLS2, PSA, PSAT, PSATD |
Species | Human |
Gene Type | protein-coding |
Description | phosphoserine aminotransferase 1 |
Other Description | endometrial progesterone-induced protein|phosphohydroxythreonine aminotransferase|phosphoserine aminotransferase |
Swissprots | Q9BQ12 Q9Y617 Q96AW2 Q5T7G6 Q5T7G5 |
Accessions | ABX55932 EAW62617 EAW62618 EAW62619 EAW62620 EAW62621 EAW62622 EAW62623 Q9Y617 AF113132 AAD42052 AK025460 AK295222 BAG58215 AK295310 BAG58289 AY131232 AAN71736 BC000971 AAH00971 BC004863 AAH04863 BC016645 AAH16645 BC018129 AAH18129 BT006840 AAP35486 DC300904 DC332195 DQ894126 ABM85052 NM_021154 NP_066977 NM_058179 NP_478059 |
Function | Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. {ECO:0000250|UniProtKB:P10658}. |
Tissue Specificity | Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon. |
Top Pathways | Glycine, serine and threonine metabolism, Vitamin B6 metabolism, Biosynthesis of amino acids, Carbon metabolism |
PSAT1 CRISPR/Cas9 KO Plasmid (h) - sc-403001 from Santa Cruz Biotechnology
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PSAT1 HDR Plasmid (h) - sc-403001-HDR from Santa Cruz Biotechnology
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PSAT1 Double Nickase Plasmid (h) - sc-403001-NIC from Santa Cruz Biotechnology
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PSAT1 Double Nickase Plasmid (h2) - sc-403001-NIC-2 from Santa Cruz Biotechnology
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PSAT1 CRISPR Activation Plasmid (h) - sc-403001-ACT from Santa Cruz Biotechnology
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PSAT1 CRISPR Activation Plasmid (h2) - sc-403001-ACT-2 from Santa Cruz Biotechnology
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PSAT1 Lentiviral Activation Particles (h) - sc-403001-LAC from Santa Cruz Biotechnology
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PSAT1 Lentiviral Activation Particles (h2) - sc-403001-LAC-2 from Santa Cruz Biotechnology
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PSAT1 siRNA (h) - sc-92619 from Santa Cruz Biotechnology
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PSAT1 shRNA Plasmid (h) - sc-92619-SH from Santa Cruz Biotechnology
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PSAT1 shRNA (h) Lentiviral Particles - sc-92619-V from Santa Cruz Biotechnology
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PSAT1 RNAi - H00029968-R01 from Novus Biologicals
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MISSION® esiRNA - EHU064011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17563 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17563 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07680 from Sigma-Aldrich
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PSAT1 siRNA (Human) - CRH9306 from Cohesion Biosciences
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PSAT1 RNAi - H00029968-R02 from Novus Biologicals
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shRNA set against Human PSAT1 (NM_021154.3) - SHH384788 from Creative biogene
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shRNA set against Human PSAT1(NM_021154.3) - SHR145642 from Creative biogene
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shRNA set against Human PSAT1(NM_058179.2) - SHR145678 from Creative biogene
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PSAT1 CRISPR/Cas9 KO Plasmid (h2) - sc-403001-KO-2 from Santa Cruz Biotechnology
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PSAT1 HDR Plasmid (h2) - sc-403001-HDR-2 from Santa Cruz Biotechnology
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PSAT1 shRNA Plasmid (Human) - CHH9306 from Cohesion Biosciences
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PSAT1 miRNA 3'UTR clone - MiUTR1H-08352 from Creative biogene
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