| Gene Symbol |
EIF4E2
|
| Entrez Gene |
9470
|
| Alt Symbol |
4E-LP, 4EHP, EIF4EL3, IF4e
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation initiation factor 4E family member 2
|
| Other Description |
eIF-4E type 2|eIF4E-like cap-binding protein|eIF4E-like protein 4E-LP|eukaryotic translation initiation factor 4E homologous protein|eukaryotic translation initiation factor 4E type 2|eukaryotic translation initiation factor 4E-like 3|mRNA cap-binding protein type 3
|
| Swissprots |
O75349 B8ZZJ9 O60573
|
| Accessions |
AAY24105 EAW71007 EAW71008 EAW71009 EAW71010 O60573 AB209519 BAD92756 AF038957 AAC39871 AF047695 AAC18565 AF068117 AAC19374 AK022518 BAG51083 AK027239 AK303802 BAG64756 BC000360 BC005392 AAH05392 BC005874 AAH05874 BC021226 AAH21226 BC021690 AAH21690 BG029258 BG913475 BM018173 CB994873 CD684451 DA201209 DA408433 DA592245 DA992544 W80980 XM_005246975 XP_005247032 XM_011512206 XP_011510508 NM_001276336 NP_001263265 NM_001276337 NP_001263266 NM_001282958 NP_001269887 NM_004846 NP_004837
|
| Function |
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
|
| Top Pathways |
Insulin signaling pathway, RNA transport, PI3K-Akt signaling pathway, mTOR signaling pathway
|