| Gene Symbol |
KIR2DL1
|
| Entrez Gene |
3802
|
| Alt Symbol |
CD158A, KIR-K64, KIR221, NKAT, NKAT-1, NKAT1, p58.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
|
| Other Description |
CD158 antigen-like family member A|MHC class I NK cell receptor|killer Ig receptor|killer cell immunoglobulin-like receptor 2DL1|killer inhibitory receptor 2-2-1|natural killer-associated transcript 1|p58 NK cell inhibitory receptor NKR-K6|p58 NK receptor CL-42/47.11|p58 killer cell inhibitory receptor KIR-K64|p58 natural killer cell receptor clones CL-42/47.11|p58.1 MHC class-I-specific NK receptor
|
| Swissprots |
Q32WE6 P43626 Q6IST4 O43470
|
| Accessions |
AAD24474 ABD38575 ABF13296 ADJ94526 ADJ94540 ADJ94556 ADJ94592 ADJ94605 ADJ94623 ADJ94638 ADJ94653 ADJ94671 ADJ94687 AGG79420 AGG79421 AGG79423 AJI81043 P43626 AF022045 AAB95318 AF135560 AAD48768 AF285431 AAG34922 AF285432 AAG34923 AY366237 AAR16195 AY366238 AAR16196 AY366239 AAR16197 AY366240 AAR16198 AY366241 AAR16199 AY388471 AAR26324 AY789055 AAX23100 AY789056 AAX23101 BC069344 AAH69344 HQ447501 ADQ31987 KJ699235 AIE89873 L41267 AAA69868 U24076 AAC50335 U24078 AAC50337 U96189 AAB54119 XM_011526939 XP_011525241 XM_011547137 XP_011545439 XM_011547143 XP_011545445 XM_011547146 XP_011545448 XM_011547148 XP_011545450 XM_011547155 XP_011545457 XM_011547163 XP_011545465 XM_011547543 XP_011545845 XM_011547545 XP_011545847 XM_011547556 XP_011545858 XM_011547559 XP_011545861 XM_011547568 XP_011545870 XM_011547575 XP_011545877 XM_011547806 XP_011546108 XM_011547809 XP_011546111 XM_011547810 XP_011546112 XM_011548561 XP_011546863 XM_011548706 XP_011547008 NM_014218 NP_055033
|
| Function |
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. {ECO:0000269|PubMed:18604210}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation
|