Gene Symbol | MYH6 |
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Entrez Gene | 4624 |
Alt Symbol | ASD3, CMD1EE, CMH14, MYHC, MYHCA, SSS3, alpha-MHC |
Species | Human |
Gene Type | protein-coding |
Description | myosin, heavy chain 6, cardiac muscle, alpha |
Other Description | myHC-alpha|myosin heavy chain 6|myosin heavy chain, cardiac muscle alpha isoform|myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)|myosin-6 |
Swissprots | Q14907 Q13943 P13533 Q14906 D9YZU2 A2RTX1 |
Accessions | AAA60386 AAA60387 ADL14490 CAA79675 EAW66154 EAW66155 P13533 AF056928 AAC13489 AK309494 BC117511 AAI17512 BC132667 AAI32668 BX501231 D00943 BAA00791 DA566231 M21664 AAA36344 X56181 CAA39642 NM_002471 NP_002462 |
Function | Muscle contraction. |
Subcellular Location | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. |
Top Pathways | Tight junction, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes |
MYH6 CRISPR/Cas9 KO Plasmid (h) - sc-400351 from Santa Cruz Biotechnology
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MYH6 HDR Plasmid (h) - sc-400351-HDR from Santa Cruz Biotechnology
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MYH6 Double Nickase Plasmid (h) - sc-400351-NIC from Santa Cruz Biotechnology
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MYH6 Double Nickase Plasmid (h2) - sc-400351-NIC-2 from Santa Cruz Biotechnology
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MYH6 CRISPR Activation Plasmid (h) - sc-400351-ACT from Santa Cruz Biotechnology
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MYH6 CRISPR Activation Plasmid (h2) - sc-400351-ACT-2 from Santa Cruz Biotechnology
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MYH6 Lentiviral Activation Particles (h) - sc-400351-LAC from Santa Cruz Biotechnology
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MYH6 Lentiviral Activation Particles (h2) - sc-400351-LAC-2 from Santa Cruz Biotechnology
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MYH6 siRNA (h) - sc-106275 from Santa Cruz Biotechnology
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MYH6 shRNA Plasmid (h) - sc-106275-SH from Santa Cruz Biotechnology
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MYH6 shRNA (h) Lentiviral Particles - sc-106275-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN14822 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14822 from Sigma-Aldrich
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MYH6 siRNA (Human) - CRH3051 from Cohesion Biosciences
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shRNA set against Human MYH6 (NM_002471.3) - SHH347812 from Creative biogene
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MYH6 CRISPR/Cas9 KO Plasmid (h2) - sc-400351-KO-2 from Santa Cruz Biotechnology
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MYH6 HDR Plasmid (h2) - sc-400351-HDR-2 from Santa Cruz Biotechnology
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Human MYH6 siRNA - orb263553 from Biorbyt
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MYH6 shRNA Plasmid (Human) - CHH3051 from Cohesion Biosciences
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