Gene Symbol |
SLURP1
|
Entrez Gene |
57152
|
Alt Symbol |
ANUP, ARS, ArsB, LY6LS, MDM
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
secreted LY6/PLAUR domain containing 1
|
Other Description |
ARS(component B)-81/S|SLURP-1|anti-neoplastic urinary protein|lymphocyte antigen 6-like secreted|secreted Ly-6/uPAR-related protein 1|secreted Ly6/uPAR related protein 1
|
Swissprots |
Q6PUA6 P55000 Q92483 Q53YJ6
|
Accessions |
CAA68237 EAW82308 P55000 AY579079 AAT01436 AY579080 AAT01437 BC069292 AAH69292 BC105133 AAI05134 BC105135 AAI05136 NM_020427 NP_065160
|
Function |
Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Granulocytes. Expressed in skin. Predominantly expressed in the granular layer of skin, notably the acrosyringium. Identified in several biological fluids such as sweat, saliva, tears, plasma and urine. {ECO:0000269|PubMed:14721776, ECO:0000269|PubMed:17008884}.
|