Gene Symbol | AP4S1 |
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Entrez Gene | 11154 |
Alt Symbol | AP47B, CLA20, CLAPS4, CPSQ6, SPG52 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 4, sigma 1 subunit |
Other Description | AP-4 adapter complex subunit sigma-1|AP-4 adaptor complex subunit sigma-1|AP-4 complex subunit sigma-1|adaptor-related protein complex 4 subunit sigma-1|clathrin-associated/assembly/adaptor protein, sigma 4|sigma-4-adaptin |
Swissprots | Q9BVE7 Q6IAQ4 Q9Y587 Q86U36 G3V2N8 |
Accessions | EAW65953 EAW65954 EAW65955 EAW65956 EAW65957 EAW65958 Q9Y587 AB030654 BAA82970 AF155159 AAD43329 AI570549 AK056928 AK098330 AK304115 BAG65016 AK316517 BAH14888 BC001259 AAH01259 BC035622 BF671561 BG702035 BT006701 AAP35347 BX247969 CAD62307 BX388185 CR457100 CAG33381 DQ890707 ABM81633 DQ893891 ABM84817 R46468 XM_005267293 XP_005267350 XM_011536371 XP_011534673 XM_011536372 XP_011534674 NM_001128126 NP_001121598 NM_001254726 NP_001241655 NM_001254727 NP_001241656 NM_001254728 NP_001241657 NM_001254729 NP_001241658 NM_007077 NP_009008 |
Function | Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. |
Subcellular Location | Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells. |
Tissue Specificity | Widely expressed. |
Top Pathways | Lysosome |
AP-4σ siRNA (h) - sc-105077 from Santa Cruz Biotechnology
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AP-4σ shRNA Plasmid (h) - sc-105077-SH from Santa Cruz Biotechnology
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AP-4σ shRNA (h) Lentiviral Particles - sc-105077-V from Santa Cruz Biotechnology
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AP4S1 RNAi - H00011154-R01 from Novus Biologicals
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MISSION® esiRNA - EHU115831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3302 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3302 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07409 from Sigma-Aldrich
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AP4S1 siRNA (Human) - CRH7635 from Cohesion Biosciences
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AP4S1 - MBS8232982 from MyBioSource
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shRNA set against Human AP4S1 (NM_007077.4) - SHH237994 from Creative biogene
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Human AP4S1 siRNA - orb268137 from Biorbyt
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AP4S1 shRNA Plasmid (Human) - CHH7635 from Cohesion Biosciences
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AP4S1 miRNA 3'UTR clone - MiUTR3H-09073 from Creative biogene
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AP4S1 miRNA 3'UTR clone - MiUTR3H-09074 from Creative biogene
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