GABRB3

Gene Symbol	GABRB3
Entrez Gene	2562
Alt Symbol	ECA5
Species	Human
Gene Type	protein-coding
Description	gamma-aminobutyric acid (GABA) A receptor, beta 3
Other Description	GABA-alpha receptor beta-2 subunit|GABAA receptor beta-3 subunit|gamma-aminobutyric acid A receptor beta 3|gamma-aminobutyric acid receptor subunit beta-3
Swissprots	B7Z2W1 F5H3D2 B7Z825 Q96FM5 P28472 Q14352 H7BYV8
Accessions	AAA52507 AAA52508 EAW57653 EAW57654 EAW57655 P28472 AK056018 AK095011 AK295167 BAH11997 AK302822 BAH13811 AK315311 BAG37715 AL120032 AW294342 BC010641 AAH10641 BC038837 BE220174 BE783170 CB162957 CD013894 CD652458 CR747353 DA138788 DB479831 DN994054 DQ891086 ABM82012 EU176555 ABW03356 KJ534842 AHW56482 M82919 AAA52511 XM_011521428 XP_011519730 NM_000814 NP_000805 NM_001191320 NP_001178249 NM_001191321 NP_001178250 NM_001278631 NP_001265560 NM_021912 NP_068712 NR_103801
Function	Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel. {ECO:0000269|PubMed:18281286, ECO:0000269|PubMed:18514161, ECO:0000269|PubMed:22243422, ECO:0000269|PubMed:22303015, ECO:0000269|PubMed:24909990}.
Subcellular Location	Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways	GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GABA A Receptor beta 3 protein fragment - ab114354 from Abcam Category Protein Source Wheat germ Species Human

GABRB3 Antibody Blocking Peptide - LS-E12558 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GABRB3 Blocking Peptide - LS-E12468 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GABRB3 Antibody Blocking Peptide - LS-E26949 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GABA-A R beta 3 Protein - H00002562-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GABRB3-Antibody-Center-Blocking-Peptide - BP2789c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GABA A Receptor beta 3 blocking peptide - GTX31010-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

GABRB3 Blocking Peptide - 33R-2752 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Gaba A Receptor beta 3 Peptide - AC21-1777-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GABRB3 - H00002562-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

GABRB3 - H00002562-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GABRB3 Peptide - 46-774P from ProSci Category Peptide Species Human

GABRB3 fusion protein - ag3009 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human GABRB3 - GABRB3-28089TH from Creative Biomart Category Protein Source Wheat germ Species Human

GABRB3, Peptide - MBS426970 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

GABRB3-Antibody-C-term-Blocking-Peptide - BP2789b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GABRB3 Peptide, Human - M34GP06023H from Creative Peptides Category Peptide Source Synthetic. Species Human

Gamma-aminobutyric acid receptor subunit beta-3 (GABRB3), Recombinant Protein - MBS955010 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GABRB3 fusion protein - Ag24748 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human GABRB3 Protein, GST-tagged - GABRB3-4647H from Creative Biomart Category Protein Source Wheat Germ Species Human

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