Gene Symbol | PEX1 |
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Entrez Gene | 5189 |
Alt Symbol | PBD1A, PBD1B, ZWS, ZWS1 |
Species | Human |
Gene Type | protein-coding |
Description | peroxisomal biogenesis factor 1 |
Other Description | Zellweger syndrome|peroxin-1|peroxisome biogenesis disorder protein 1|peroxisome biogenesis factor 1 |
Swissprots | O43933 Q96S72 Q96S73 A8KA90 B4DIM7 A4D1G3 E9PE75 Q99994 Q96S71 |
Accessions | AAB46346 EAL24149 EAL24151 EAW76840 EAW76841 EAW76842 EAW76843 EAW76844 O43933 AA490966 AB008112 BAA85162 AB052090 BAB59061 AB052091 BAB59062 AB052092 BAB59063 AB052093 BAB59064 AB052094 BAB59065 AB209355 BAD92592 AF026086 AAB87880 AF030356 AAB99758 AI377121 AK292955 BAF85644 AK293757 BAG57177 AK293848 BAG57246 AK295686 BAG58539 BC035575 AAH35575 DA313282 DB461678 DC370317 DQ890921 ABM81847 XM_005250433 XP_005250490 XR_242246 NM_000466 NP_000457 NM_001282677 NP_001269606 NM_001282678 NP_001269607 |
Function | Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. |
Subcellular Location | Cytoplasm. Peroxisome membrane. Note=Associated with peroxisomal membranes. |
Top Pathways | Peroxisome |
Peroxin 1 CRISPR/Cas9 KO Plasmid (h) - sc-410929 from Santa Cruz Biotechnology
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Peroxin 1 HDR Plasmid (h) - sc-410929-HDR from Santa Cruz Biotechnology
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Peroxin 1 Double Nickase Plasmid (h) - sc-410929-NIC from Santa Cruz Biotechnology
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Peroxin 1 Double Nickase Plasmid (h2) - sc-410929-NIC-2 from Santa Cruz Biotechnology
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Peroxin 1 CRISPR Activation Plasmid (h) - sc-410929-ACT from Santa Cruz Biotechnology
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Peroxin 1 CRISPR Activation Plasmid (h2) - sc-410929-ACT-2 from Santa Cruz Biotechnology
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Peroxin 1 Lentiviral Activation Particles (h) - sc-410929-LAC from Santa Cruz Biotechnology
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Peroxin 1 Lentiviral Activation Particles (h2) - sc-410929-LAC-2 from Santa Cruz Biotechnology
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Peroxin 1 siRNA (h) - sc-44927 from Santa Cruz Biotechnology
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Peroxin 1 shRNA Plasmid (h) - sc-44927-SH from Santa Cruz Biotechnology
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Peroxin 1 shRNA (h) Lentiviral Particles - sc-44927-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU031211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16629 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16629 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05377 from Sigma-Aldrich
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PEX1 siRNA (Human) - CRH3461 from Cohesion Biosciences
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PEX1 RNAi - H00005189-R01 from Novus Biologicals
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shRNA set against Human PEX1 (NM_000466.2) - SHH373624 from Creative biogene
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shRNA set against Human PEX1(NM_000466.2) - SHR096036 from Creative biogene
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PEX1 shRNA Plasmid (Human) - CHH3461 from Cohesion Biosciences
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PEX1 miRNA 3'UTR clone - MiUTR1H-07788 from Creative biogene
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