AP1M1
| Gene Symbol | AP1M1 |
|---|---|
| Entrez Gene | 8907 |
| Alt Symbol | AP47, CLAPM2, CLTNM, MU-1A |
| Species | Human |
| Gene Type | protein-coding |
| Description | adaptor-related protein complex 1, mu 1 subunit |
| Other Description | AP-1 complex subunit mu-1|AP-mu chain family member mu1A|HA1 47 kDa subunit|adapter-related protein complex 1 subunit mu-1|adaptor protein complex AP-1 mu-1 subunit|adaptor protein complex AP-1 subunit mu-1|adaptor-related protein complex 1 mu-1 subunit|adaptor-related protein complex 1 subunit mu-1|clathrin adaptor protein AP47|clathrin assembly protein complex 1 medium chain 1|clathrin assembly protein complex 1 mu-1 medium chain 1|clathrin assembly protein complex 1, medium chain|clathrin assembly protein complex AP1, mu subunit|clathrin coat assembly protein AP47|clathrin coat-associated protein AP47|golgi adaptor AP-1 47 kDa protein|golgi adaptor HA1/AP1 adaptin mu-1 subunit|mu-adaptin 1|mu1A-adaptin |
| Swissprots | Q9BXS5 Q4TTY5 |
| Accessions | EAW84539 EAW84540 Q9BXS5 AB209808 BAD93045 AF290613 AAK28024 AK027528 BAG51337 AK293188 BAG56728 AK297824 BAG60161 BC017469 AAH17469 BQ014582 BU729646 DC386056 DQ059565 AAY54246 XM_011528399 XP_011526701 XM_011528400 XP_011526702 NM_001130524 NP_001123996 NM_032493 NP_115882 |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Subcellular Location | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Top Pathways | Lysosome |
AP-1μ1 CRISPR/Cas9 KO Plasmid (h) - sc-405695 from Santa Cruz Biotechnology
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AP-1μ1 HDR Plasmid (h) - sc-405695-HDR from Santa Cruz Biotechnology
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AP-1μ1 Double Nickase Plasmid (h) - sc-405695-NIC from Santa Cruz Biotechnology
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AP-1μ1 Double Nickase Plasmid (h2) - sc-405695-NIC-2 from Santa Cruz Biotechnology
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AP-1μ1 CRISPR Activation Plasmid (h) - sc-405695-ACT from Santa Cruz Biotechnology
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AP-1μ1 CRISPR Activation Plasmid (h2) - sc-405695-ACT-2 from Santa Cruz Biotechnology
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AP-1μ1 Lentiviral Activation Particles (h) - sc-405695-LAC from Santa Cruz Biotechnology
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AP-1μ1 Lentiviral Activation Particles (h2) - sc-405695-LAC-2 from Santa Cruz Biotechnology
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AP-1µ1 siRNA (h) - sc-97430 from Santa Cruz Biotechnology
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AP-1µ1 shRNA Plasmid (h) - sc-97430-SH from Santa Cruz Biotechnology
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AP-1µ1 shRNA (h) Lentiviral Particles - sc-97430-V from Santa Cruz Biotechnology
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AP1M1 RNAi - H00008907-R01 from Novus Biologicals
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MISSION® esiRNA - EHU013031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3282 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3282 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06646 from Sigma-Aldrich
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AP1M1 siRNA (Human) - CRH5889 from Cohesion Biosciences
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AP1M1 - MBS8225319 from MyBioSource
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shRNA set against Human AP1M1 (NM_032493.3) - SHH237770 from Creative biogene
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AP1M1 shRNA Plasmid (Human) - CHH5889 from Cohesion Biosciences
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AP1M1 miRNA 3'UTR clone - MiUTR3H-06055 from Creative biogene
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AP1M1 miRNA 3'UTR clone - MiUTR3H-06056 from Creative biogene
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