Gene Symbol | PDIA3 |
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Entrez Gene | 2923 |
Alt Symbol | ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HEL-S-269, HEL-S-93n, HsT17083, P58, PI-PLC |
Species | Human |
Gene Type | protein-coding |
Description | protein disulfide isomerase family A, member 3 |
Other Description | 58 kDa glucose-regulated protein|58 kDa microsomal protein|ER protein 57|ER protein 60|disulfide isomerase ER-60|endoplasmic reticulum P58|endoplasmic reticulum resident protein 57|endoplasmic reticulum resident protein 60|epididymis secretory protein Li 269|epididymis secretory sperm binding protein Li 93n|glucose regulated protein, 58kDa|phospholipase C-alpha|protein disulfide isomerase-associated 3|protein disulfide-isomerase A3 |
Swissprots | P30101 Q14255 Q8IYF8 Q9UMU7 Q13453 |
Accessions | AAB37397 AAC51518 CAK18760 CCD35251 EAW77234 EAW77235 EAW77236 P30101 AI769725 AK075455 BAG52144 AK075481 BAG52151 AK293249 BAG56782 BC014433 AAH14433 BC036000 AAH36000 BC071878 AAH71878 BE644608 BG826781 BM854408 D16234 BAA03759 D83485 BAA11928 DQ893070 ABM83996 DQ896325 ABM87324 EU668338 ACF94491 FJ224330 ACI46022 U42068 AAC50331 Z49835 CAA89996 NM_005313 NP_005304 |
Subcellular Location | Endoplasmic reticulum. Endoplasmic reticulum lumen {ECO:0000250}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Detected in the flagellum and head region of spermatozoa (at protein level). {ECO:0000269|PubMed:20400973}. |
Top Pathways | Protein processing in endoplasmic reticulum, Antigen processing and presentation |
ERp57 CRISPR/Cas9 KO Plasmid (h) - sc-401497 from Santa Cruz Biotechnology
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ERp57 HDR Plasmid (h) - sc-401497-HDR from Santa Cruz Biotechnology
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ERp57 Double Nickase Plasmid (h) - sc-401497-NIC from Santa Cruz Biotechnology
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ERp57 Double Nickase Plasmid (h2) - sc-401497-NIC-2 from Santa Cruz Biotechnology
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ERp57 CRISPR Activation Plasmid (h) - sc-401497-ACT from Santa Cruz Biotechnology
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ERp57 CRISPR Activation Plasmid (h2) - sc-401497-ACT-2 from Santa Cruz Biotechnology
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ERp57 Lentiviral Activation Particles (h) - sc-401497-LAC from Santa Cruz Biotechnology
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ERp57 Lentiviral Activation Particles (h2) - sc-401497-LAC-2 from Santa Cruz Biotechnology
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ERp57 siRNA (h) - sc-35341 from Santa Cruz Biotechnology
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ERp57 shRNA Plasmid (h) - sc-35341-SH from Santa Cruz Biotechnology
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ERp57 shRNA (h) Lentiviral Particles - sc-35341-V from Santa Cruz Biotechnology
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ERp57 siRNA (h2) - sc-44299 from Santa Cruz Biotechnology
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ERp57 shRNA Plasmid (h2) - sc-44299-SH from Santa Cruz Biotechnology
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ERp57 shRNA (h2) Lentiviral Particles - sc-44299-V from Santa Cruz Biotechnology
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ERp57 siRNA (r) - sc-270455 from Santa Cruz Biotechnology
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ERp57 shRNA Plasmid (r) - sc-270455-SH from Santa Cruz Biotechnology
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ERp57 shRNA (r) Lentiviral Particles - sc-270455-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU109271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16559 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16559 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09473 from Sigma-Aldrich
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PDIA3 siRNA (Human) - CRH1976 from Cohesion Biosciences
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shRNA set against Human PDIA3 (NM_005313.4) - SHH372792 from Creative biogene
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shRNA set against Human PDIA3(NM_005313.4) - SHR101958 from Creative biogene
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Human PDIA3 siRNA - orb262478 from Biorbyt
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