Gene Symbol | Grb2 |
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Entrez Gene | 14784 |
Alt Symbol | AA408164, Ash |
Species | Mouse |
Gene Type | protein-coding |
Description | growth factor receptor bound protein 2 |
Other Description | SH2/SH3 adapter GRB2|adapter protein GRB2|growth factor receptor-bound protein 2 |
Swissprots | Q60631 Q61240 |
Accessions | EDL34515 EDL34516 EDL34517 Q60631 AK077750 AK079087 AK148148 BAE28376 AK153557 BAE32093 AK155800 BAE33439 AK166142 BAE38595 AK170845 BAE42068 AK172002 AK177056 AK180406 AK181485 AK184348 AK192421 AK192819 AK194267 AK195178 AK195957 AK196023 AK196107 AK196759 AK202005 AK208766 AK211391 AK212651 AK215138 AK216513 AK217191 AK217799 BC052377 AAH52377 BC085254 AAH85254 D85748 BAA12862 U07617 AAB40022 NM_008163 NP_032189 |
Function | Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Golgi apparatus {ECO:0000269|PubMed:11571277}. |
Top Pathways | Alcoholism, Focal adhesion, Insulin signaling pathway, Prolactin signaling pathway, MicroRNAs in cancer |
GRB2 CRISPR/Cas9 KO Plasmid (m) - sc-420668 from Santa Cruz Biotechnology
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GRB2 HDR Plasmid (m) - sc-420668-HDR from Santa Cruz Biotechnology
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GRB2 Double Nickase Plasmid (m) - sc-420668-NIC from Santa Cruz Biotechnology
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GRB2 Double Nickase Plasmid (m2) - sc-420668-NIC-2 from Santa Cruz Biotechnology
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GRB2 CRISPR Activation Plasmid (m) - sc-420668-ACT from Santa Cruz Biotechnology
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GRB2 CRISPR Activation Plasmid (m2) - sc-420668-ACT-2 from Santa Cruz Biotechnology
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GRB2 Lentiviral Activation Particles (m) - sc-420668-LAC from Santa Cruz Biotechnology
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GRB2 Lentiviral Activation Particles (m2) - sc-420668-LAC-2 from Santa Cruz Biotechnology
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GRB2 siRNA (m) - sc-29335 from Santa Cruz Biotechnology
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GRB2 shRNA Plasmid (m) - sc-29335-SH from Santa Cruz Biotechnology
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GRB2 shRNA (m) Lentiviral Particles - sc-29335-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU173921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN32820 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32820 from Sigma-Aldrich
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GRB2 siRNA (Mouse) - CRM1673 from Cohesion Biosciences
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GRB2 - MBS8202384 from MyBioSource
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shRNA set against Mouse GRB2 (NM_008163.3) - SHH307594 from Creative biogene
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GRB2 shRNA Plasmid (Mouse) - CHM1673 from Cohesion Biosciences
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GRB2 miRNA 3'UTR clone - MiUTR1M-05359 from Creative biogene
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