Gene Symbol |
Agtr2
|
Entrez Gene |
11609
|
Alt Symbol |
AI316812, AW107640
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
angiotensin II receptor, type 2
|
Other Description |
AT2 receptor|angiotensin II type-2 receptor|type-2 angiotensin II receptor
|
Swissprots |
P35374
|
Accessions |
AAA82184 EDL00719 EDL00720 P35374 AK086334 BAC39650 AK140941 BAE24525 BC003811 AAH03811 L32840 AAB49539 S67465 AAB29336 U04828 AAC52128 XM_006527555 XP_006527618 NM_007429 NP_031455
|
Function |
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. {ECO:0000269|PubMed:15539617}.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15539617}; Multi-pass membrane protein {ECO:0000269|PubMed:15539617}.
|
Tissue Specificity |
Expressed at highest levels in adrenal gland and uterus. {ECO:0000269|PubMed:15539617}.
|
Top Pathways |
Adrenergic signaling in cardiomyocytes, Renin-angiotensin system, Neuroactive ligand-receptor interaction
|