Gene Symbol | Agtr2 |
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Entrez Gene | 11609 |
Alt Symbol | AI316812, AW107640 |
Species | Mouse |
Gene Type | protein-coding |
Description | angiotensin II receptor, type 2 |
Other Description | AT2 receptor|angiotensin II type-2 receptor|type-2 angiotensin II receptor |
Swissprots | P35374 |
Accessions | AAA82184 EDL00719 EDL00720 P35374 AK086334 BAC39650 AK140941 BAE24525 BC003811 AAH03811 L32840 AAB49539 S67465 AAB29336 U04828 AAC52128 XM_006527555 XP_006527618 NM_007429 NP_031455 |
Function | Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. {ECO:0000269|PubMed:15539617}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15539617}; Multi-pass membrane protein {ECO:0000269|PubMed:15539617}. |
Tissue Specificity | Expressed at highest levels in adrenal gland and uterus. {ECO:0000269|PubMed:15539617}. |
Top Pathways | Adrenergic signaling in cardiomyocytes, Renin-angiotensin system, Neuroactive ligand-receptor interaction |
AT 2 CRISPR/Cas9 KO Plasmid (m) - sc-419050 from Santa Cruz Biotechnology
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AT 2 HDR Plasmid (m) - sc-419050-HDR from Santa Cruz Biotechnology
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AT 2 Double Nickase Plasmid (m) - sc-419050-NIC from Santa Cruz Biotechnology
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AT 2 Double Nickase Plasmid (m2) - sc-419050-NIC-2 from Santa Cruz Biotechnology
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AT 2 CRISPR Activation Plasmid (m) - sc-419050-ACT from Santa Cruz Biotechnology
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AT 2 CRISPR Activation Plasmid (m2) - sc-419050-ACT-2 from Santa Cruz Biotechnology
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AT 2 Lentiviral Activation Particles (m) - sc-419050-LAC from Santa Cruz Biotechnology
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AT 2 Lentiviral Activation Particles (m2) - sc-419050-LAC-2 from Santa Cruz Biotechnology
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AT 2 siRNA (m) - sc-29753 from Santa Cruz Biotechnology
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AT 2 shRNA Plasmid (m) - sc-29753-SH from Santa Cruz Biotechnology
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AT 2 shRNA (m) Lentiviral Particles - sc-29753-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN26423 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26423 from Sigma-Aldrich
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AGTR2 siRNA (Mouse) - CRM0109 from Cohesion Biosciences
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AGTR2 - MBS8208151 from MyBioSource
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AT2 CRISPR/Cas9 KO Plasmid (m2) - sc-419050-KO-2 from Santa Cruz Biotechnology
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AT2 HDR Plasmid (m2) - sc-419050-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Mouse AGTR2 (NM_007429.5) - SHH233534 from Creative biogene
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AGTR2 shRNA Plasmid (Mouse) - CHM0109 from Cohesion Biosciences
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