| Gene Symbol |
CYTH1
|
| Entrez Gene |
9267
|
| Alt Symbol |
B2-1, CYTOHESIN-1, D17S811E, PSCD1, SEC7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytohesin 1
|
| Other Description |
PH, SEC7 and coiled-coil domain-containing protein 1|SEC7 homolog B2-1|cytoadhesin 1|cytohesin-1|homolog of secretory protein SEC7|pleckstrin homology, Sec7 and coiled-coil domains 1
|
| Swissprots |
Q15438 Q9P124 Q9P123 B7Z1T4 A6NFW7
|
| Accessions |
AAF37737 AAF37738 EAW89530 EAW89531 EAW89532 Q15438 AA030002 AF054997 AK091369 AK123894 AK293894 BAH11620 AK296914 BAG59469 AK307917 AK311535 AK316075 BAH14446 AK316277 BAH14648 AL832791 BC038385 AAH38385 BC050452 AAH50452 BX339155 DA125333 EU832306 ACE87563 EU832390 ACE86875 HY049953 M85169 AAA36602 XM_006722182 XP_006722245 XM_011525475 XP_011523777 XM_011525476 XP_011523778 XM_011525477 XP_011523779 XM_011525478 XP_011523780 XR_934600 NM_001292018 NP_001278947 NM_001292019 NP_001278948 NM_004762 NP_004753 NM_017456 NP_059430
|
| Function |
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. {ECO:0000269|PubMed:10652308, ECO:0000269|PubMed:9653114}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}. Cytoplasm, cytosol {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Endocytosis
|
