Gene Symbol | SKIV2L |
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Entrez Gene | 6499 |
Alt Symbol | 170A, DDX13, HLP, SKI2, SKI2W, SKIV2, THES2 |
Species | Human |
Gene Type | protein-coding |
Description | superkiller viralicidic activity 2-like (S. cerevisiae) |
Other Description | helicase SKI2W|helicase-like protein |
Swissprots | Q15476 O15005 Q12902 Q5ST66 Q15477 |
Accessions | AAA93258 AAA93259 AAB67978 AAC78607 AIU44409 CAA67024 CAB89307 EAX03554 EAX03555 EAX03556 EAX03557 Q15477 AB209605 BAD92842 AK293881 BAG57270 AK297230 BAG59713 AK299967 BAG61793 AK303302 BAG64376 AK303448 BAG64493 AL529319 BC015758 AAH15758 BE395851 BG396326 DQ892087 ABM83013 EU176680 ABW03481 U09877 AAB52523 Z48796 CAA88733 XM_006715168 XP_006715231 XM_006725497 XP_006725560 XM_011514815 XP_011513117 XM_011547275 XP_011545577 XM_011547678 XP_011545980 XM_011548076 XP_011546378 XM_011548265 XP_011546567 XM_011548460 XP_011546762 XR_430936 XR_430997 XR_431014 XR_431044 XR_926301 XR_952212 XR_952642 XR_952947 XR_953010 XR_953083 NM_006929 NP_008860 |
Function | Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). |
Subcellular Location | Nucleus {ECO:0000305}. Cytoplasm {ECO:0000305}. |
Top Pathways | RNA degradation |
SKIV2L CRISPR/Cas9 KO Plasmid (h) - sc-407733 from Santa Cruz Biotechnology
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SKIV2L HDR Plasmid (h) - sc-407733-HDR from Santa Cruz Biotechnology
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SKIV2L Double Nickase Plasmid (h) - sc-407733-NIC from Santa Cruz Biotechnology
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SKIV2L Double Nickase Plasmid (h2) - sc-407733-NIC-2 from Santa Cruz Biotechnology
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SKIV2L CRISPR Activation Plasmid (h) - sc-407733-ACT from Santa Cruz Biotechnology
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SKIV2L CRISPR Activation Plasmid (h2) - sc-407733-ACT-2 from Santa Cruz Biotechnology
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SKIV2L Lentiviral Activation Particles (h) - sc-407733-LAC from Santa Cruz Biotechnology
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SKIV2L Lentiviral Activation Particles (h2) - sc-407733-LAC-2 from Santa Cruz Biotechnology
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SKIV2L siRNA (h) - sc-95203 from Santa Cruz Biotechnology
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SKIV2L shRNA Plasmid (h) - sc-95203-SH from Santa Cruz Biotechnology
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SKIV2L shRNA (h) Lentiviral Particles - sc-95203-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN19381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19381 from Sigma-Aldrich
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SKIV2L siRNA (Human) - CRH4395 from Cohesion Biosciences
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SKIV2L RNAi - H00006499-R02 from Novus Biologicals
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SKIV2L - MBS8218289 from MyBioSource
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shRNA set against Human SKIV2L (NM_006929.4) - SHH408028 from Creative biogene
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shRNA set against Human SKIV2L(NM_006929.4) - SHR193020 from Creative biogene
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Human SKIV2L siRNA - orb264897 from Biorbyt
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SKIV2L shRNA Plasmid (Human) - CHH4395 from Cohesion Biosciences
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SKIV2L miRNA 3'UTR clone - MiUTR1H-09422 from Creative biogene
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