| Gene Symbol | GNG3 |
|---|---|
| Entrez Gene | 2785 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanine nucleotide binding protein (G protein), gamma 3 |
| Other Description | NBP gamma-3|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3|guanine nucleotide-binding protein gamma-3 subunit |
| Swissprots | P63215 B2R4S7 |
| Accessions | AAF04567 EAW74082 P63215 AF075042 AF087900 AAP97199 AF092129 AAD40371 AF493871 AAM12585 AK311933 BAG34874 BC015563 AAH15563 CK004020 DA123305 DQ891890 ABM82816 DQ895076 ABM86002 XM_006718500 XP_006718563 XM_006718501 XP_006718564 NM_012202 NP_036334 |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
| Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Top Pathways | Glutamatergic synapse, Dopaminergic synapse, GABAergic synapse, Taste transduction, Morphine addiction |