Gene Symbol | GNG3 |
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Entrez Gene | 2785 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma 3 |
Other Description | NBP gamma-3|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3|guanine nucleotide-binding protein gamma-3 subunit |
Swissprots | P63215 B2R4S7 |
Accessions | AAF04567 EAW74082 P63215 AF075042 AF087900 AAP97199 AF092129 AAD40371 AF493871 AAM12585 AK311933 BAG34874 BC015563 AAH15563 CK004020 DA123305 DQ891890 ABM82816 DQ895076 ABM86002 XM_006718500 XP_006718563 XM_006718501 XP_006718564 NM_012202 NP_036334 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Glutamatergic synapse, Dopaminergic synapse, GABAergic synapse, Taste transduction, Morphine addiction |
G γ 3 CRISPR/Cas9 KO Plasmid (h) - sc-406978 from Santa Cruz Biotechnology
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G γ 3 HDR Plasmid (h) - sc-406978-HDR from Santa Cruz Biotechnology
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G γ 3 Double Nickase Plasmid (h) - sc-406978-NIC from Santa Cruz Biotechnology
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G γ 3 Double Nickase Plasmid (h2) - sc-406978-NIC-2 from Santa Cruz Biotechnology
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G γ 3 CRISPR Activation Plasmid (h) - sc-406978-ACT from Santa Cruz Biotechnology
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G γ 3 CRISPR Activation Plasmid (h2) - sc-406978-ACT-2 from Santa Cruz Biotechnology
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G γ 3 Lentiviral Activation Particles (h) - sc-406978-LAC from Santa Cruz Biotechnology
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G γ 3 Lentiviral Activation Particles (h2) - sc-406978-LAC-2 from Santa Cruz Biotechnology
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G γ 3 siRNA (h) - sc-41776 from Santa Cruz Biotechnology
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G γ 3 shRNA Plasmid (h) - sc-41776-SH from Santa Cruz Biotechnology
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G γ 3 shRNA (h) Lentiviral Particles - sc-41776-V from Santa Cruz Biotechnology
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G gamma3 RNAi - H00002785-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9428 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9428 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03293 from Sigma-Aldrich
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GNG3 siRNA (Human) - CRH1857 from Cohesion Biosciences
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GNG3 - MBS8224306 from MyBioSource
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shRNA set against Human GNG3 (NM_012202.4) - SHH304894 from Creative biogene
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Human GNG3 siRNA - orb262359 from Biorbyt
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GNG3 shRNA Plasmid (Human) - CHH1857 from Cohesion Biosciences
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GNG3 miRNA 3'UTR clone - MiUTR3H-10322 from Creative biogene
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