Gene Symbol |
ATP12A
|
Entrez Gene |
100008669
|
Alt Symbol |
-
|
Species |
Rabbit
|
Gene Type |
protein-coding
|
Description |
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
|
Other Description |
H+,K+-ATPase alpha 2 subunit|H+,K+-ATPase alpha 2c subunit|H,K-ATPase alpha2 subunit|HK alpha 2|hydrogen/potassium-exchanging ATPase 12A|non-gastric H(+)/K(+) ATPase subunit alpha|potassium-transporting ATPase alpha chain 2|proton pump
|
Swissprots |
Q9TV52 Q9TV53 Q9TSI2
|
Accessions |
AAS76541 Q9TV52 AF023128 AAB80941 AF023129 AAC13887 AF106063 AAD11800 GBCH01035529 U24216 AAA92291 XM_008259638 XP_008257860 XR_517228 NM_001082027 NP_001075496
|
Function |
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Found in the skin, kidney, distal colon and brain. In the kidney it is found in the connecting tubule, cortical collecting duct and outer medullary collecting duct while in the brain it is specific to choroid plexus and cortex. {ECO:0000269|PubMed:9872395}.
|
Top Pathways |
Oxidative phosphorylation
|