CACNA2D1

Gene Symbol	CACNA2D1
Entrez Gene	781
Alt Symbol	CACNA2, CACNL2A, CCHL2A, LINC01112, lncRNA-N3
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, alpha 2/delta subunit 1
Other Description	calcium channel, L type, alpha 2 polypeptide|dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit|voltage-dependent calcium channel subunit alpha-2/delta-1|voltage-gated calcium channel subunit alpha-2/delta-1
Swissprots	Q9UD82 Q17R45 Q9UD80 Q9UD81 P54289
Accessions	AAC78619 AAD20938 AAD51454 AAF03259 AAF19234 EAW76990 P54289 AI924415 AK055040 AK092048 AK299838 BAH13144 AL707206 AL833141 BC051339 BC117468 AAI17469 BC117470 AAI17471 BG055272 BI545104 BP258070 BU501177 M76559 AAA51903 XM_005250570 XP_005250627 XM_005250572 XP_005250629 XM_005250573 XP_005250630 XM_005250574 XP_005250631 XM_006716118 XP_006716181 XM_006716119 XP_006716182 XM_006716120 XP_006716183 XM_006716121 XP_006716184 XM_011516570 XP_011514872 XM_011516571 XP_011514873 XM_011516572 XP_011514874 XM_011516573 XP_011514875 XM_011516574 XP_011514876 NM_000722 NP_000713 NM_001302890 NP_001289819
Function	The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta. {ECO:0000269|PubMed:1309651, ECO:0000269|PubMed:8107964}.
Top Pathways	MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CACNA2D1 Antibody Blocking Peptide - LS-E12445 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CACNA2D1 Antibody Blocking Peptide - LS-E26363 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CACNA2D1 Antibody Blocking Peptide - LS-E9730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CACNA2D1-Antibody-N-term-Blocking-Peptide - BP8699a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CACNA2D1 blocking peptide - GTX89045-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human CACNA2D1 protein - orb244063 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CACNA2D1 protein - orb245773 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

CACNA2D1 Blocking Peptide - 33R-7178 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Calcium Channel L type DHPR alpha 2 Subunit Peptide - AC21-1198-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CACNA2D1 Peptide - 45-350P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human CACNA2D1 - CACNA2D1-161H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Cacna2d1 (E139) Peptide - BS2857P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Voltage-dependent calcium channel subunit alpha-2/delta-1(CACN - CSB-YP004407HU CSB-BP004407HU CSB-MP004407HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Voltage-dependent calcium channel subunit alpha-2/delta-1(CACNA2D1),partial - CSB-EP004407HU from Cusabio Category Protein Source E.coli Species Human

Voltage-dependent calcium channel subunit alpha-2/delta-1(CACNA2D1) ,partial, Recombinant Protein - MBS959628 from MyBioSource Category Protein Prices $835.00, $835.00, $950.00, $1,055.00, $1,170.00, $1,170.00, $1,390.00, $1,620.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CACNA2D1, Peptide - MBS426764 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human CACNA2D1 protein, Trx-His-SUMO-tagged - CACNA2D1-29H from Creative Biomart Category Protein Source E.coli Species Human

CACNA2D1 Recombinant Protein Antigen - NBP1-86683PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

CACNA2D1 Recombinant Protein Antigen - NBP1-86682PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CACNA2D1 Peptide, Human - M34GP02262H from Creative Peptides Category Peptide Source Synthetic. Species Human

CACNA2D1 Recombinant Protein (OPCA01496) - OPCA01496 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

CACNA2D1 Recombinant Protein (OPCA02612) - OPCA02612 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Voltage-dependent calcium channel subunit alpha-2/delta-1 - AP70105 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant human Voltage-dependent calcium channel subunit alpha-2/delta-1 - AP72469 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Recombinant Human Voltage-dependent calcium channel subunit alpha-2/delta-1(CACNA2D1),partial - CSB-YP004407HU1 from Cusabio Category Protein Source Yeast Species Human

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