Gene Symbol | SPG20 |
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Entrez Gene | 23111 |
Alt Symbol | SPARTIN, TAHCCP1 |
Species | Human |
Gene Type | protein-coding |
Description | spastic paraplegia 20 (Troyer syndrome) |
Other Description | spartin|trans-activated by hepatitis C virus core protein 1 |
Swissprots | Q9H1T2 Q86Y67 Q8N0X7 Q9H1T3 O60349 |
Accessions | AAK71883 AAM76672 CAH25953 EAX08558 EAX08559 EAX08560 EAX08561 EAX08562 EAX08563 Q8N0X7 AA137195 AB011182 BAA25536 AK001949 BAG50995 AK002207 BAG51030 AK057764 AK291724 BAF84413 AK302119 BAG63497 AY038359 AAK72374 AY123329 AAM76671 BC026284 BC047083 AAH47083 BQ719410 BU622545 BX648004 DA347686 DA507821 DA710623 DB282617 XM_005266313 XP_005266370 XM_005266314 XP_005266371 XM_005266315 XP_005266372 XM_005266316 XP_005266373 XM_005266317 XP_005266374 XM_011535012 XP_011533314 XR_941540 NM_001142294 NP_001135766 NM_001142295 NP_001135767 NM_001142296 NP_001135768 NM_015087 NP_055902 |
Function | May be implicated in endosomal trafficking, or microtubule dynamics, or both. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19580544}. Note=Transiently associated with endosomes. |
Tissue Specificity | Ubiquitously expressed, with highest levels of expression detected in adipose tissue. |
Spartin CRISPR/Cas9 KO Plasmid (h) - sc-407769 from Santa Cruz Biotechnology
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Spartin HDR Plasmid (h) - sc-407769-HDR from Santa Cruz Biotechnology
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Spartin Double Nickase Plasmid (h) - sc-407769-NIC from Santa Cruz Biotechnology
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Spartin Double Nickase Plasmid (h2) - sc-407769-NIC-2 from Santa Cruz Biotechnology
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Spartin CRISPR Activation Plasmid (h) - sc-407769-ACT from Santa Cruz Biotechnology
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Spartin CRISPR Activation Plasmid (h2) - sc-407769-ACT-2 from Santa Cruz Biotechnology
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Spartin Lentiviral Activation Particles (h) - sc-407769-LAC from Santa Cruz Biotechnology
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Spartin Lentiviral Activation Particles (h2) - sc-407769-LAC-2 from Santa Cruz Biotechnology
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Spartin siRNA (h) - sc-61601 from Santa Cruz Biotechnology
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Spartin shRNA Plasmid (h) - sc-61601-SH from Santa Cruz Biotechnology
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Spartin shRNA (h) Lentiviral Particles - sc-61601-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU076581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20462 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20462 from Sigma-Aldrich
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SPG20 siRNA (Human) - CRH8005 from Cohesion Biosciences
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SPG20 - MBS8223284 from MyBioSource
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shRNA set against Human SPG20 (NM_015087.4) - SHH416564 from Creative biogene
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Human SPG20 siRNA - orb268507 from Biorbyt
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SPG20 shRNA Plasmid (Human) - CHH8005 from Cohesion Biosciences
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