Gene Symbol | Hlx |
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Entrez Gene | 15284 |
Alt Symbol | Hlx1 |
Species | Mouse |
Gene Type | protein-coding |
Description | H2.0-like homeobox |
Other Description | H2.0-like homeo box 1|H2.0-like homeobox protein|homeobox protein HLX1 |
Swissprots | Q61670 |
Accessions | AAG22584 EDL13081 EDL13082 Q61670 AK036435 AK154090 BAE32368 BB664380 BC050146 AAH50146 BC064068 AAH64068 X58250 CAA41204 NM_008250 NP_032276 |
Function | Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis. {ECO:0000269|PubMed:12055627}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in Th1 cells, CD8-positive T-cells, B-cells and NK cells. {ECO:0000269|PubMed:12055627}. |
HLX1 CRISPR/Cas9 KO Plasmid (m) - sc-420868 from Santa Cruz Biotechnology
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HLX1 HDR Plasmid (m) - sc-420868-HDR from Santa Cruz Biotechnology
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HLX1 Double Nickase Plasmid (m) - sc-420868-NIC from Santa Cruz Biotechnology
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HLX1 Double Nickase Plasmid (m2) - sc-420868-NIC-2 from Santa Cruz Biotechnology
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HLX1 CRISPR Activation Plasmid (m) - sc-420868-ACT from Santa Cruz Biotechnology
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HLX1 CRISPR Activation Plasmid (m2) - sc-420868-ACT-2 from Santa Cruz Biotechnology
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HLX1 Lentiviral Activation Particles (m) - sc-420868-LAC from Santa Cruz Biotechnology
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HLX1 Lentiviral Activation Particles (m2) - sc-420868-LAC-2 from Santa Cruz Biotechnology
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HLX1 siRNA (m) - sc-62473 from Santa Cruz Biotechnology
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HLX1 shRNA Plasmid (m) - sc-62473-SH from Santa Cruz Biotechnology
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HLX1 shRNA (m) Lentiviral Particles - sc-62473-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU030561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33327 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33327 from Sigma-Aldrich
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HLX siRNA (Mouse) - CRM1841 from Cohesion Biosciences
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HLX - MBS8237548 from MyBioSource
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shRNA set against Mouse HLX (NM_008250.2) - SHH313165 from Creative biogene
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HLX1 CRISPR/Cas9 KO Plasmid (m2) - sc-420868-KO-2 from Santa Cruz Biotechnology
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HLX1 HDR Plasmid (m2) - sc-420868-HDR-2 from Santa Cruz Biotechnology
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Mouse HLX siRNA - orb281317 from Biorbyt
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HLX shRNA Plasmid (Mouse) - CHM1841 from Cohesion Biosciences
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