| Gene Symbol |
EVA1A
|
| Entrez Gene |
84141
|
| Alt Symbol |
FAM176A, TMEM166
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eva-1 homolog A (C. elegans)
|
| Other Description |
family with sequence similarity 176, member A|protein FAM176A|protein eva-1 homolog A|transmembrane protein 166
|
| Swissprots |
Q9HC41 Q9H8M9 D6W5J3
|
| Accessions |
AAY14774 CAE91766 EAW99591 EAW99592 EAW99593 EAW99594 Q9H8M9 AF177337 AAG17981 AK023453 BAB14580 AW016395 BC016157 AAH16157 BC063016 AAH63016 BE892427 BP276065 CR457314 CAG33595 NM_001135032 NP_001128504 NM_032181 NP_115557
|
| Function |
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. {ECO:0000269|PubMed:17492404, ECO:0000269|PubMed:19029833}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:17492404}; Single-pass membrane protein {ECO:0000269|PubMed:17492404}. Lysosome membrane {ECO:0000269|PubMed:17492404}; Single-pass membrane protein {ECO:0000269|PubMed:17492404}.
|
| Tissue Specificity |
Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. {ECO:0000269|PubMed:17492404}.
|