| Gene Symbol |
GPR17
|
| Entrez Gene |
2840
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 17
|
| Other Description |
G-protein coupled receptor 17|P2Y-like receptor|R12|UDP/CysLT receptor|uracil nucleotide/cysteinyl leukotriene receptor
|
| Swissprots |
A8K9L0 B2R9X0 Q13304 Q8N5S7 Q9UDZ6 Q9UE21
|
| Accessions |
AAB16746 EAW95337 Q13304 AK126849 BAG54380 AK292725 BAF85414 AK313949 BAG36667 BC013202 BC031653 AAH31653 BC039595 BX538082 CAD98006 DA154324 DA314295 DA366480 DA390892 DQ892453 ABM83379 DQ895665 ABM86591 JF810891 AEP43758 Y12546 CAA73144 Z94154 CAB08107 Z94155 CAB08108 NM_001161415 NP_001154887 NM_001161416 NP_001154888 NM_001161417 NP_001154889 NM_005291 NP_005282
|
| Function |
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. {ECO:0000269|PubMed:16990797}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. {ECO:0000269|PubMed:16990797}.
|
![Western Blot: GPR17 Overexpression Lysate (Adult Normal) [NBP2-10474] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR17.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5332_GPR17%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10474-img0001.jpg)