| Gene Symbol |
SERAC1
|
| Entrez Gene |
84947
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine active site containing 1
|
| Other Description |
protein SERAC1|serine active site-containing protein 1
|
| Swissprots |
Q6PKF3 Q49AT1 Q96JX3 Q5VTX3
|
| Accessions |
EAW47664 Q96JX3 AA128978 AK023656 AK027823 BAB55393 AK125878 BC001705 AAH01705 BC028594 AAH28594 BC048335 BC060795 BX648104 DA232092 DB046171 XM_006715586 XP_006715649 XM_011536196 XP_011534498 XM_011536197 XP_011534499 XM_011536198 XP_011534500 XR_942606 NM_032861 NP_116250 NR_073096
|
| Function |
Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation- acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway. {ECO:0000269|PubMed:22683713}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000269|PubMed:22683713}. Mitochondrion {ECO:0000269|PubMed:22683713}. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface.
|
| Tissue Specificity |
Widely expressed, with predominant expression in fetal skeletal muscle and adult brain. In the brain, highest levels are found in the frontal and occipital cortices, cerebellum and hippocampus. {ECO:0000269|PubMed:22683713}.
|