Gene Symbol | Hexb |
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Entrez Gene | 15212 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | hexosaminidase B |
Other Description | N-acetyl-beta-glucosaminidase subunit beta|beta-N-acetylhexosaminidase subunit beta|beta-hexosaminidase subunit beta|hexosaminidase subunit B |
Swissprots | P20060 |
Accessions | AAA74738 AAB60667 EDL00872 EDL00873 EDL00874 P20060 AK151149 BAE30155 AK159134 BAE34846 AK159178 BAE34877 AK160560 BAE35874 AK168825 BAE40652 AK185127 AK194154 AK209131 AK212361 BC140360 AAI40361 BC146503 AAI46504 BY145642 CD775639 U07633 AAA18776 Y00964 CAA68781 NM_010422 NP_034552 |
Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation |
HEXB CRISPR/Cas9 KO Plasmid (m) - sc-420838 from Santa Cruz Biotechnology
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HEXB HDR Plasmid (m) - sc-420838-HDR from Santa Cruz Biotechnology
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HEXB Double Nickase Plasmid (m) - sc-420838-NIC from Santa Cruz Biotechnology
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HEXB Double Nickase Plasmid (m2) - sc-420838-NIC-2 from Santa Cruz Biotechnology
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HEXB CRISPR Activation Plasmid (m) - sc-420838-ACT from Santa Cruz Biotechnology
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HEXB CRISPR Activation Plasmid (m2) - sc-420838-ACT-2 from Santa Cruz Biotechnology
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HEXB Lentiviral Activation Particles (m) - sc-420838-LAC from Santa Cruz Biotechnology
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HEXB Lentiviral Activation Particles (m2) - sc-420838-LAC-2 from Santa Cruz Biotechnology
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HEXB siRNA (m) - sc-60786 from Santa Cruz Biotechnology
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HEXB shRNA Plasmid (m) - sc-60786-SH from Santa Cruz Biotechnology
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HEXB shRNA (m) Lentiviral Particles - sc-60786-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU009111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33200 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33200 from Sigma-Aldrich
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HEXB siRNA (Mouse) - CRM1811 from Cohesion Biosciences
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HEXB - MBS8217131 from MyBioSource
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shRNA set against Mouse HEXB (NM_010422.2) - SHH311781 from Creative biogene
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Mouse HEXB siRNA - orb281287 from Biorbyt
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HEXB shRNA Plasmid (Mouse) - CHM1811 from Cohesion Biosciences
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