Gene Symbol |
HAUS6
|
Entrez Gene |
54801
|
Alt Symbol |
Dgt6, FAM29A
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
HAUS augmin-like complex, subunit 6
|
Other Description |
HAUS augmin-like complex subunit 6|dim gamma-tubulin homolog|family with sequence similarity 29, member A
|
Swissprots |
B3KPK4 Q9H950 Q14CB6 B4DX82 Q05CG1 Q9HCJ8 Q6NZX5 Q14CD9 Q6IQ10 Q9H998 Q96FN0 Q2TA91 Q8IZQ4 Q9NXT8 Q7Z4H7
|
Accessions |
EAW58652 Q7Z4H7 AB046794 BAB13400 AF533709 AAQ09022 AF537091 AAN05700 AK000067 BAA90922 AK022964 BAB14334 AK023068 BAB14388 AK056458 BAG51716 AK225209 AK301852 BAG63294 AL832495 AM393468 CAL38345 BC010632 AAH10632 BC026178 AAH26178 BC065935 AAH65935 BC071625 AAH71625 BC111041 AAI11042 BC113981 AAI13982 BC114492 AAI14493 DB010660 XM_011517935 XP_011516237 NM_001270890 NP_001257819 NM_017645 NP_060115
|
Function |
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. {ECO:0000269|PubMed:19029337, ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
|
Subcellular Location |
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
|