Gene Symbol | IL2RA |
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Entrez Gene | 3559 |
Alt Symbol | CD25, IDDM10, IL2R, TCGFR, p55 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 2 receptor, alpha |
Other Description | IL-2 receptor subunit alpha|IL-2R subunit alpha|TAC antigen|interleukin-2 receptor subunit alpha |
Swissprots | P01589 Q5W007 |
Accessions | AAA59144 AAA59162 AAA67527 AAS55572 CAA26906 CAK26553 CBX47444 CCF77061 EAW86412 EAW86413 EAW86414 P01589 AF008556 AAB63458 AK223313 BAD97033 AK313847 BAG36576 BC152889 AAI52890 BC156627 AAI56628 CD701954 CR996090 K03122 AAB59535 M14098 AAA59142 X01057 CAA25525 XM_005252446 XP_005252503 NM_000417 NP_000408 NM_001308242 NP_001295171 NM_001308243 NP_001295172 |
Function | Receptor for interleukin-2. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, Endocytosis, HTLV-I infection |
IL-2Rα CRISPR/Cas9 KO Plasmid (h) - sc-401262 from Santa Cruz Biotechnology
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IL-2Rα HDR Plasmid (h) - sc-401262-HDR from Santa Cruz Biotechnology
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IL-2Rα Double Nickase Plasmid (h) - sc-401262-NIC from Santa Cruz Biotechnology
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IL-2Rα Double Nickase Plasmid (h2) - sc-401262-NIC-2 from Santa Cruz Biotechnology
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IL-2Rα CRISPR Activation Plasmid (h) - sc-401262-ACT from Santa Cruz Biotechnology
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IL-2Rα CRISPR Activation Plasmid (h2) - sc-401262-ACT-2 from Santa Cruz Biotechnology
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IL-2Rα Lentiviral Activation Particles (h) - sc-401262-LAC from Santa Cruz Biotechnology
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IL-2Rα Lentiviral Activation Particles (h2) - sc-401262-LAC-2 from Santa Cruz Biotechnology
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IL-2Rα siRNA (h) - sc-29367 from Santa Cruz Biotechnology
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IL-2Rα shRNA Plasmid (h) - sc-29367-SH from Santa Cruz Biotechnology
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IL-2Rα shRNA (h) Lentiviral Particles - sc-29367-V from Santa Cruz Biotechnology
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CD25/IL-2 R alpha RNAi - H00003559-R02 from Novus Biologicals
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MISSION® esiRNA - EHU078131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10623 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10623 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09013 from Sigma-Aldrich
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IL2RA siRNA (Human) - CRH2377 from Cohesion Biosciences
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IL2RA - MBS8228381 from MyBioSource
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shRNA set against Human IL2RA (NM_000417.2) - SHH318853 from Creative biogene
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Human IL2RA siRNA - orb262879 from Biorbyt
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IL2RA shRNA Plasmid (Human) - CHH2377 from Cohesion Biosciences
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IL2RA miRNA 3'UTR clone - MiUTR4H-TG04474 from Creative biogene
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