Gene Symbol | Npy1r |
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Entrez Gene | 18166 |
Alt Symbol | Npyr, Y1-R |
Species | Mouse |
Gene Type | protein-coding |
Description | neuropeptide Y receptor Y1 |
Other Description | NPY-1 receptor|NPY1-R|neuropeptide Y receptor subtype|neuropeptide Y receptor type 1 |
Swissprots | Q61993 Q04573 |
Accessions | AAA12819 CAA79157 CBH19833 EDL28699 EDL28700 Q04573 AK132397 BAE21145 AK162898 D63818 BAA09887 D63819 BAA09888 XM_006509594 XP_006509657 XM_006509595 XP_006509658 XM_006509596 XP_006509659 NM_010934 NP_035064 |
Function | Receptor for neuropeptide Y and peptide YY. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | The alpha form is highly expressed in the brain, heart, kidney, spleen, skeletal muscle, and lung, whereas the beta receptor mRNA was not detected in these tissues. However, the beta form is expressed in mouse embryonic developmental stage (7 and 11 days), bone marrow cells and several hematopoietic cell lines. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
NPY1-R CRISPR/Cas9 KO Plasmid (m) - sc-421952 from Santa Cruz Biotechnology
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NPY1-R HDR Plasmid (m) - sc-421952-HDR from Santa Cruz Biotechnology
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NPY1-R Double Nickase Plasmid (m) - sc-421952-NIC from Santa Cruz Biotechnology
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NPY1-R Double Nickase Plasmid (m2) - sc-421952-NIC-2 from Santa Cruz Biotechnology
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NPY1-R CRISPR Activation Plasmid (m) - sc-421952-ACT from Santa Cruz Biotechnology
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NPY1-R CRISPR Activation Plasmid (m2) - sc-421952-ACT-2 from Santa Cruz Biotechnology
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NPY1-R Lentiviral Activation Particles (m) - sc-421952-LAC from Santa Cruz Biotechnology
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NPY1-R Lentiviral Activation Particles (m2) - sc-421952-LAC-2 from Santa Cruz Biotechnology
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NPY1-R siRNA (m) - sc-36098 from Santa Cruz Biotechnology
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NPY1-R shRNA Plasmid (m) - sc-36098-SH from Santa Cruz Biotechnology
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NPY1-R shRNA (m) Lentiviral Particles - sc-36098-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN36639 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36639 from Sigma-Aldrich
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NPY1R siRNA (Mouse) - CRM2830 from Cohesion Biosciences
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shRNA set against Mouse NPY1R (NM_010934.4) - SHH354552 from Creative biogene
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Mouse NPY1R siRNA - orb282306 from Biorbyt
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NPY1R shRNA Plasmid (Mouse) - CHM2830 from Cohesion Biosciences
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