Gene Symbol | ITIH4 |
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Entrez Gene | 3700 |
Alt Symbol | GP120, H4P, IHRP, ITI-HC4, ITIHL1, PK-120, PK120 |
Species | Human |
Gene Type | protein-coding |
Description | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
Other Description | ITI heavy chain H4|inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)|inter-alpha-inhibitor heavy chain 4|inter-alpha-trypsin inhibitor family heavy chain-related protein|inter-alpha-trypsin inhibitor heavy chain H4|inter-alpha-trypsin inhibitor, heavy chain-like, 1|plasma kallikrein-sensitive glycoprotein 120 |
Swissprots | Q9P190 Q15135 B7Z545 Q14624 Q9UQ54 E9PGN5 |
Accessions | AAD05198 EAW65264 EAW65265 Q14624 AB209388 BAD92625 AI217735 AK298407 BAH12780 AK298412 BAH12781 AK298429 BAH12787 AK303769 BAH14043 AW291001 BC136392 AAI36393 BC136393 AAI36394 BX477542 BX647322 D38595 BAA07602 DC412911 NM_001166449 NP_001159921 NM_002218 NP_002209 |
Function | Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. {ECO:0000269|PubMed:19263524}. |
Subcellular Location | Secreted. |
Tissue Specificity | Liver specific. {ECO:0000269|PubMed:7775381, ECO:0000269|PubMed:7805892}. |
ITI-H4 CRISPR/Cas9 KO Plasmid (h) - sc-403358 from Santa Cruz Biotechnology
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ITI-H4 HDR Plasmid (h) - sc-403358-HDR from Santa Cruz Biotechnology
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ITI-H4 Double Nickase Plasmid (h) - sc-403358-NIC from Santa Cruz Biotechnology
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ITI-H4 Double Nickase Plasmid (h2) - sc-403358-NIC-2 from Santa Cruz Biotechnology
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ITI-H4 CRISPR Activation Plasmid (h) - sc-403358-ACT from Santa Cruz Biotechnology
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ITI-H4 CRISPR Activation Plasmid (h2) - sc-403358-ACT-2 from Santa Cruz Biotechnology
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ITI-H4 Lentiviral Activation Particles (h) - sc-403358-LAC from Santa Cruz Biotechnology
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ITI-H4 Lentiviral Activation Particles (h2) - sc-403358-LAC-2 from Santa Cruz Biotechnology
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ITI-H4 siRNA (h) - sc-45402 from Santa Cruz Biotechnology
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ITI-H4 shRNA Plasmid (h) - sc-45402-SH from Santa Cruz Biotechnology
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ITI-H4 shRNA (h) Lentiviral Particles - sc-45402-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU075821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10825 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10825 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03873 from Sigma-Aldrich
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ITIH4 siRNA (Human) - CRH2489 from Cohesion Biosciences
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ITIH4 - MBS8207620 from MyBioSource
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ITIH4 - MBS8201244 from MyBioSource |
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ITI-H4 CRISPR/Cas9 KO Plasmid (h2) - sc-403358-KO-2 from Santa Cruz Biotechnology
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ITI-H4 HDR Plasmid (h2) - sc-403358-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human IH (NM_002218.4) - SHH317937 from Creative biogene
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Human ITIH4 siRNA - orb262991 from Biorbyt
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ITIH4 shRNA Plasmid (Human) - CHH2489 from Cohesion Biosciences
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ITIH4 miRNA 3'UTR clone - MiUTR3H-03479 from Creative biogene
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