Gene Symbol | HRASLS |
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Entrez Gene | 57110 |
Alt Symbol | A-C1, H-REV107, HRASLS1, HRSL1, HSD28 |
Species | Human |
Gene Type | protein-coding |
Description | HRAS-like suppressor |
Other Description | H-REV107 protein-related protein|HRAS-like suppressor 1|phospholipase A|phospholipid-metabolizing enzyme A-C1 |
Swissprots | Q9HDD0 D2KX19 |
Accessions | EAW78078 EAW78079 Q9HDD0 AB030816 BAB08110 AB510981 BAI63210 AY251533 AAP20056 BC048095 AAH48095 BX098792 XM_011513033 XP_011511335 XM_011513034 XP_011511336 XM_011513035 XP_011511337 XM_011513036 XP_011511338 XM_011513037 XP_011511339 NM_020386 NP_065119 |
Function | Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs. {ECO:0000269|PubMed:21880860}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Abundantly expressed in testis, skeletal muscle, brain, and heart. {ECO:0000269|PubMed:21880860}. |
HRASLS CRISPR/Cas9 KO Plasmid (h) - sc-410058 from Santa Cruz Biotechnology
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HRASLS HDR Plasmid (h) - sc-410058-HDR from Santa Cruz Biotechnology
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HRASLS Double Nickase Plasmid (h) - sc-410058-NIC from Santa Cruz Biotechnology
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HRASLS Double Nickase Plasmid (h2) - sc-410058-NIC-2 from Santa Cruz Biotechnology
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HRASLS CRISPR Activation Plasmid (h) - sc-410058-ACT from Santa Cruz Biotechnology
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HRASLS CRISPR Activation Plasmid (h2) - sc-410058-ACT-2 from Santa Cruz Biotechnology
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HRASLS Lentiviral Activation Particles (h) - sc-410058-LAC from Santa Cruz Biotechnology
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HRASLS Lentiviral Activation Particles (h2) - sc-410058-LAC-2 from Santa Cruz Biotechnology
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HRASLS siRNA (h) - sc-78330 from Santa Cruz Biotechnology
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HRASLS shRNA Plasmid (h) - sc-78330-SH from Santa Cruz Biotechnology
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HRASLS shRNA (h) Lentiviral Particles - sc-78330-V from Santa Cruz Biotechnology
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HRAS like suppressor RNAi - H00057110-R01 from Novus Biologicals
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MISSION® esiRNA - EHU009181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10291 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11922 from Sigma-Aldrich
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shRNA set against Human HRASLS (NM_020386.4) - SHH314785 from Creative biogene
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HRASLS miRNA 3'UTR clone - MiUTR3H-08498 from Creative biogene
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