Gene Symbol | RHOF |
---|---|
Entrez Gene | 54509 |
Alt Symbol | ARHF, RIF |
Species | Human |
Gene Type | protein-coding |
Description | ras homolog family member F (in filopodia) |
Other Description | ras homolog gene family, member F (in filopodia)|rho family GTPase Rif|rho in filopodia|rho-related GTP-binding protein RhoF |
Swissprots | Q9NXH6 Q8WVB1 Q9HBH0 |
Accessions | CAI61864 EAW98278 EAW98279 Q9HBH0 AF239923 AAG24952 AK000254 BAA91034 AK130459 AK289482 BAF82171 BC018208 AAH18208 BC018721 BC032529 BC043395 BG574506 BM830620 BQ053707 BQ422695 BU527972 CA426077 NM_019034 NP_061907 |
Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton. |