Gene Symbol | ADAMTS8 |
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Entrez Gene | 11095 |
Alt Symbol | ADAM-TS8, METH2 |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 8|ADAM-TS 8|ADAMTS-8|METH-2|METH-8|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 |
Swissprots | Q9NZS0 Q9UP79 |
Accessions | EAW67783 EAW67784 EAW67785 Q9UP79 AB209717 BAD92954 AF060153 AAD48081 AF175283 AAF25806 AK123706 BAG53941 BC089435 AAH89435 BC113874 AAI13875 BC114624 AAI14625 BM988619 NM_007037 NP_008968 |
Function | Has anti-angiogenic properties. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Highly expressed in adult and fetal lung, lower expression in brain, placenta, heart, stomach and fetal brain and kidney. |
ADAMTS-8 CRISPR/Cas9 KO Plasmid (h) - sc-405463 from Santa Cruz Biotechnology
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ADAMTS-8 HDR Plasmid (h) - sc-405463-HDR from Santa Cruz Biotechnology
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ADAMTS-8 Double Nickase Plasmid (h) - sc-405463-NIC from Santa Cruz Biotechnology
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ADAMTS-8 Double Nickase Plasmid (h2) - sc-405463-NIC-2 from Santa Cruz Biotechnology
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ADAMTS-8 CRISPR Activation Plasmid (h) - sc-405463-ACT from Santa Cruz Biotechnology
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ADAMTS-8 CRISPR Activation Plasmid (h2) - sc-405463-ACT-2 from Santa Cruz Biotechnology
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ADAMTS-8 Lentiviral Activation Particles (h) - sc-405463-LAC from Santa Cruz Biotechnology
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ADAMTS-8 Lentiviral Activation Particles (h2) - sc-405463-LAC-2 from Santa Cruz Biotechnology
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ADAMTS-8 siRNA (h) - sc-43603 from Santa Cruz Biotechnology
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ADAMTS-8 shRNA Plasmid (h) - sc-43603-SH from Santa Cruz Biotechnology
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ADAMTS-8 shRNA (h) Lentiviral Particles - sc-43603-V from Santa Cruz Biotechnology
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ADAMTS8 RNAi - H00011095-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2838 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2838 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05643 from Sigma-Aldrich
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ADAMTS8 siRNA (Human) - CRH7587 from Cohesion Biosciences
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ADAMTS8 - MBS8225378 from MyBioSource
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shRNA set against Human ADAMTS8 (NM_007037.4) - SHH231922 from Creative biogene
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shRNA set against Human ADAMTS8(NM_007037.4) - SHG040183 from Creative biogene
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Human ADAMTS8 siRNA - orb268089 from Biorbyt
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ADAMTS8 shRNA Plasmid (Human) - CHH7587 from Cohesion Biosciences
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ADAMTS8 miRNA 3'UTR clone - MiUTR1H-00177 from Creative biogene
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