USP48
| Gene Symbol | USP48 |
|---|---|
| Entrez Gene | 84196 |
| Alt Symbol | RAP1GA1, USP31 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin specific peptidase 48 |
| Other Description | deubiquitinating enzyme 48|ubiquitin carboxyl-terminal hydrolase 48|ubiquitin specific protease 31|ubiquitin thioesterase 48|ubiquitin thiolesterase 48|ubiquitin-specific-processing protease 48 |
| Swissprots | Q9H5N3 Q96IQ3 B7ZKS7 Q9NXR0 Q9H5T7 Q2M3I4 Q5SZI4 Q6NX53 Q86UV5 Q9NUJ6 Q96F64 Q8N3F6 Q5T3T5 |
| Accessions | EAW94987 EAW94988 EAW94989 EAW94990 EAW94991 EAW94992 Q86UV5 AF502942 AAP30832 AI248244 AK000110 BAA90950 AK002190 BAA92128 AK021830 AK026707 BAB15533 AK074247 AK226150 AK315005 AL834375 CAD39038 BC007326 AAH07326 BC011576 BC013567 AAH13567 BC067261 AAH67261 BC103724 AAI03725 BC104896 AAI04897 BC143343 AAI43344 BC143349 AAI43350 BC143354 AAI43355 BM462540 BP238468 BQ027743 CA436959 XM_005246009 XP_005246066 XM_006710951 XP_006711014 XM_006710955 XP_006711018 XM_011542262 XP_011540564 XM_011542263 XP_011540565 XM_011542264 XP_011540566 XM_011542265 XP_011540567 XM_011542266 XP_011540568 XM_011542267 XP_011540569 XM_011542268 XP_011540570 XM_011542269 XP_011540571 NM_001032730 NP_001027902 NM_032236 NP_115612 |
| Function | Recognizes and hydrolyzes the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. {ECO:0000269|PubMed:16214042}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16214042}. Nucleus {ECO:0000269|PubMed:16214042}. |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:15354349, ECO:0000269|PubMed:16214042}. |
USP48 CRISPR/Cas9 KO Plasmid (h) - sc-409580 from Santa Cruz Biotechnology
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USP48 HDR Plasmid (h) - sc-409580-HDR from Santa Cruz Biotechnology
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USP48 Double Nickase Plasmid (h) - sc-409580-NIC from Santa Cruz Biotechnology
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USP48 Double Nickase Plasmid (h2) - sc-409580-NIC-2 from Santa Cruz Biotechnology
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USP48 CRISPR Activation Plasmid (h) - sc-409580-ACT from Santa Cruz Biotechnology
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USP48 CRISPR Activation Plasmid (h2) - sc-409580-ACT-2 from Santa Cruz Biotechnology
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USP48 Lentiviral Activation Particles (h) - sc-409580-LAC from Santa Cruz Biotechnology
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USP48 Lentiviral Activation Particles (h2) - sc-409580-LAC-2 from Santa Cruz Biotechnology
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USP48 siRNA (h) - sc-76865 from Santa Cruz Biotechnology
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USP48 shRNA Plasmid (h) - sc-76865-SH from Santa Cruz Biotechnology
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USP48 shRNA (h) Lentiviral Particles - sc-76865-V from Santa Cruz Biotechnology
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USP31 RNAi - H00057478-R01 from Novus Biologicals
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USP48 RNAi - H00084196-R02 from Novus Biologicals
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USP48 RNAi - H00084196-R01 from Novus Biologicals
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MISSION® esiRNA - EHU081621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22597 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22597 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12508 from Sigma-Aldrich
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USP48 siRNA (Human) - CRJ3348 from Cohesion Biosciences
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USP48 - MBS8225670 from MyBioSource
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shRNA set against Human USP48 (NM_032236.5) - SHH441688 from Creative biogene
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shRNA set against Human USP48(NM_032236.5) - SHL117984 from Creative biogene
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shRNA set against Human USP48(NM_001032730.1) - SHL118020 from Creative biogene
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Human USP48 siRNA - orb273849 from Biorbyt
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USP48 shRNA Plasmid (Human) - CHJ3348 from Cohesion Biosciences
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