| Gene Symbol |
HID1
|
| Entrez Gene |
283987
|
| Alt Symbol |
C17orf28, DMC1, HID-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
HID1 domain containing
|
| Other Description |
HID1 domain-containing protein|UPF0663 transmembrane protein C17orf28|down-regulated in multiple cancers 1|downregulated in multiple cancer 1|protein HID1|protein hid-1 homolog
|
| Swissprots |
Q9NT34 Q8N5L6 Q8IV36 Q8TE83
|
| Accessions |
CCQ43734 EAW89217 EAW89218 EAW89219 EAW89220 EAW89221 Q8IV36 AK074401 BAB85070 AK075111 BAC11407 AK095565 AK125514 AK304081 BAG64988 AL137556 CAB70810 BC032219 AAH32219 BC035372 AAH35372 BX496609 DA336027 JF432821 ADZ16038 XM_005257226 XP_005257283 XM_005257227 XP_005257284 XM_011524615 XP_011522917 NM_030630 NP_085133
|
| Function |
May play an important role in the development of cancers in a broad range of tissues. {ECO:0000269|PubMed:11281419}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21337012}. Golgi apparatus membrane {ECO:0000269|PubMed:21337012}; Lipid- anchor {ECO:0000269|PubMed:21337012}. Note=Shuttles between the cytosol and the Golgi apparatus.
|
| Tissue Specificity |
Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines. {ECO:0000269|PubMed:11281419, ECO:0000269|PubMed:21337012}.
|