| Gene Symbol |
TACC2
|
| Entrez Gene |
10579
|
| Alt Symbol |
AZU-1, ECTACC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transforming, acidic coiled-coil containing protein 2
|
| Other Description |
anti zuai-1|transforming acidic coiled-coil-containing protein 2
|
| Swissprots |
Q9NZR5 Q86WG7 Q86WG6 Q4VXL7 Q9BVQ1 O95359 Q5U5T7 Q4VXL3 Q4VXL6 Q4VXL0 Q8TCK9 Q9NZ41
|
| Accessions |
EAW49324 EAW49325 O95359 AF095791 AAC64968 AF176646 AAF63433 AF220152 AAF29537 AF528098 AAO62629 AF528099 AAO62630 AK027066 AK056743 AK075097 AK094848 AK095371 AK295631 BAH12132 AL713712 CAD28509 AL833304 BC000999 AAH00999 BC010219 BC015736 BC029124 BC031036 BC039311 AAH39311 BC141837 BC142673 BC144599 AAI44600 BC144600 AAI44601 BC150627 AAI50628 CN420638 DR001720 R46074 XM_005269388 XP_005269445 XM_005269389 XP_005269446 XM_005269390 XP_005269447 XM_005269391 XP_005269448 XM_005269392 XP_005269449 XM_005269393 XP_005269450 XM_005269394 XP_005269451 XM_005269395 XP_005269452 XM_005269396 XP_005269453 XM_005269397 XP_005269454 XM_005269399 XP_005269456 XM_006717548 XP_006717611 XM_006717552 XP_006717615 XM_006717553 XP_006717616 XM_006717554 XP_006717617 XM_011539126 XP_011537428 XM_011539127 XP_011537429 XM_011539128 XP_011537430 XM_011539129 XP_011537431 XM_011539130 XP_011537432 XM_011539131 XP_011537433 XM_011539132 XP_011537434 XM_011539133 XP_011537435 XM_011539134 XP_011537436 XM_011539135 XP_011537437 NM_001291876 NP_001278805 NM_001291877 NP_001278806 NM_001291878 NP_001278807 NM_001291879 NP_001278808 NM_006997 NP_008928 NM_206860 NP_996742 NM_206861 NP_996743 NM_206862 NP_996744
|
| Function |
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. {ECO:0000250, ECO:0000269|PubMed:10749935}.
|
| Subcellular Location |
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
|
| Tissue Specificity |
Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea. {ECO:0000269|PubMed:11161455, ECO:0000269|PubMed:12620397}.
|