Gene Symbol | UTS2R |
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Entrez Gene | 2837 |
Alt Symbol | GPR14, UR-2-R, UTR, UTR2 |
Species | Human |
Gene Type | protein-coding |
Description | urotensin 2 receptor |
Other Description | G protein-coupled receptor 14|G-protein coupled receptor 14|UR-II-R|urotensin II receptor|urotensin-2 receptor |
Swissprots | B2RMV8 Q9UKP6 |
Accessions | AAD55578 EAW89768 Q9UKP6 BC136490 AAI36491 NM_018949 NP_061822 |
Function | High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:14550283}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Most abundant expression in the heart and pancreas. |
Top Pathways | Neuroactive ligand-receptor interaction |
GPR14 CRISPR/Cas9 KO Plasmid (h) - sc-402393 from Santa Cruz Biotechnology
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GPR14 HDR Plasmid (h) - sc-402393-HDR from Santa Cruz Biotechnology
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GPR14 Double Nickase Plasmid (h) - sc-402393-NIC from Santa Cruz Biotechnology
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GPR14 Double Nickase Plasmid (h2) - sc-402393-NIC-2 from Santa Cruz Biotechnology
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GPR14 CRISPR Activation Plasmid (h) - sc-402393-ACT from Santa Cruz Biotechnology
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GPR14 CRISPR Activation Plasmid (h2) - sc-402393-ACT-2 from Santa Cruz Biotechnology
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GPR14 Lentiviral Activation Particles (h) - sc-402393-LAC from Santa Cruz Biotechnology
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GPR14 Lentiviral Activation Particles (h2) - sc-402393-LAC-2 from Santa Cruz Biotechnology
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Urotensin-II R/GPR14 RNAi - H00002837-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN22624 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22624 from Sigma-Aldrich
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UTS2R siRNA (Human) - CRH1901 from Cohesion Biosciences
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UTS2R - MBS8203522 from MyBioSource
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shRNA set against Human UTS2R (NM_018949.1) - SHH442024 from Creative biogene
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shRNA set against Human UTS2R(NM_018949.1) - SHL119604 from Creative biogene
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UTS2R shRNA Plasmid (Human) - CHH1901 from Cohesion Biosciences
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UTS2R miRNA 3'UTR clone - MiUTR1H-11084 from Creative biogene
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