Gene Symbol | CENPQ |
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Entrez Gene | 55166 |
Alt Symbol | C6orf139, CENP-Q |
Species | Human |
Gene Type | protein-coding |
Description | centromere protein Q |
Other Description | - |
Swissprots | Q7L2Z9 Q6IN61 A8KAF1 Q9NVS5 |
Accessions | EAX04332 EAX04333 Q7L2Z9 AA460110 AA811376 AI039464 AK001407 BAA91672 AK293016 BAF85705 BC016279 AAH16279 BI768787 XM_005249205 XP_005249262 XM_011514723 XP_011513025 NM_018132 NP_060602 |
Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. {ECO:0000269|PubMed:16622420}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16622420}. Chromosome, centromere {ECO:0000269|PubMed:16622420}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
CENPQ CRISPR/Cas9 KO Plasmid (h) - sc-417922 from Santa Cruz Biotechnology
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CENPQ HDR Plasmid (h) - sc-417922-HDR from Santa Cruz Biotechnology
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CENPQ Double Nickase Plasmid (h) - sc-417922-NIC from Santa Cruz Biotechnology
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CENPQ Double Nickase Plasmid (h2) - sc-417922-NIC-2 from Santa Cruz Biotechnology
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CENPQ CRISPR Activation Plasmid (h) - sc-417922-ACT from Santa Cruz Biotechnology
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CENPQ CRISPR Activation Plasmid (h2) - sc-417922-ACT-2 from Santa Cruz Biotechnology
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CENPQ Lentiviral Activation Particles (h) - sc-417922-LAC from Santa Cruz Biotechnology
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CENPQ Lentiviral Activation Particles (h2) - sc-417922-LAC-2 from Santa Cruz Biotechnology
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CENPQ siRNA (h) - sc-95491 from Santa Cruz Biotechnology
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CENPQ shRNA Plasmid (h) - sc-95491-SH from Santa Cruz Biotechnology
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CENPQ shRNA (h) Lentiviral Particles - sc-95491-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5952 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5952 from Sigma-Aldrich
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CENPQ siRNA (Human) - CRJ0520 from Cohesion Biosciences
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CENPQ RNAi - H00055166-R01 from Novus Biologicals
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CENPQ - MBS8219550 from MyBioSource
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shRNA set against Human CENPQ (NM_018132.3) - SHH261737 from Creative biogene
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shRNA set against Human CENPQ(NM_018132.3) - SHG168415 from Creative biogene
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CENPQ shRNA Plasmid (Human) - CHJ0520 from Cohesion Biosciences
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CENPQ miRNA 3'UTR clone - MiUTR1H-02044 from Creative biogene
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