CYP46A1

Gene Symbol	CYP46A1
Entrez Gene	10858
Alt Symbol	CP46, CYP46
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 46, subfamily A, polypeptide 1
Other Description	CH24H|cholesterol 24-hydroxylase|cytochrome P450 46A1|cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
Swissprots	Q9Y6A2 E7EQG9 Q8N2B0 B4DHP8
Accessions	EAW81678 Q9Y6A2 AB209749 BAD92986 AF094480 AAD41244 AK090886 BAC03539 AK295216 BAG58210 BC022539 AAH22539 XM_005267274 XP_005267331 XM_011536364 XP_011534666 XM_011536365 XP_011534667 NM_006668 NP_006659
Function	Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole. {ECO:0000269|PubMed:18621681, ECO:0000269|PubMed:20667828}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Tissue Specificity	Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample but its expression increases linearly with age.
Top Pathways	Primary bile acid biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cholesterol 24-hydroxylase (CYP46A1), Human, ELISA Kit - E01C2252 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/ml

CYP46A1 (Human) IP-WB Antibody Pair - H00010858-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Cholesterol 24 hydroxylase (CYP46A1), ELISA Kit - MBS7230539 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7236637 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7235102 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7201860 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7223895 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7225947 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7207772 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7250018 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7204707 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7240604 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7244483 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-hydroxylase (CYP46A1), ELISA Kit - MBS7248345 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cytochrome P450, family 46, subfamily A, polypeptide 1, ELISA Kit - MBS9336649 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 1.56ng/ml-50ng/ml.

ELISA Kit for Cytochrome P450 46A1 (CYP46A1) - SED536Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.33ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Cytochrome P450 46A1 (CYP46A1) - SED536Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.33ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Cytochrome P450 46A1 (CYP46A1) ELISA Kit - EKU09170 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.33 ng/mL Range 0.781-50 ng/mL

Human CYP46A1 ELISA Kit - E008217 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

CYP46A1 ELISA Kit (Human) (OKCD01771) - OKCD01771 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.27 ng/mL Range 0.781 - 50 ng/mL

Cholesterol 24-Hydroxylase (CYP46A1), ELISA Kit - MBS9390576 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-Hydroxylase (CYP46A1), ELISA Kit - MBS9390584 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-Hydroxylase (CYP46A1), ELISA Kit - MBS9390569 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-Hydroxylase (CYP46A1), ELISA Kit - MBS9390572 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cholesterol 24-Hydroxylase (CYP46A1), ELISA Kit - MBS9390570 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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