Gene Symbol | TRMT6 |
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Entrez Gene | 51605 |
Alt Symbol | CGI-09, GCD10, Gcd10p |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 6 |
Other Description | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6|tRNA methyltransferase 6 homolog|tRNA(m1A58)MTase subunit TRM6 |
Swissprots | Q9UJA5 Q76P92 B4DUV6 Q9ULR7 Q9Y2Z8 Q9BQV5 |
Accessions | EAX10406 EAX10407 Q9UJA5 AB032979 BAA86467 AF132943 AAD27718 AI291549 AK000613 AK300812 BAG62468 AK308648 AK309205 AL556917 BC001262 AAH01262 DC348968 NM_001281467 NP_001268396 NM_015939 NP_057023 |
Function | Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. {ECO:0000269|PubMed:16043508}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in brain, liver, testis and ovary. {ECO:0000269|PubMed:10574461}. |
TRMT6 CRISPR/Cas9 KO Plasmid (h) - sc-412224 from Santa Cruz Biotechnology
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TRMT6 HDR Plasmid (h) - sc-412224-HDR from Santa Cruz Biotechnology
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TRMT6 Double Nickase Plasmid (h) - sc-412224-NIC from Santa Cruz Biotechnology
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TRMT6 Double Nickase Plasmid (h2) - sc-412224-NIC-2 from Santa Cruz Biotechnology
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TRMT6 CRISPR Activation Plasmid (h) - sc-412224-ACT from Santa Cruz Biotechnology
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TRMT6 CRISPR Activation Plasmid (h2) - sc-412224-ACT-2 from Santa Cruz Biotechnology
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TRMT6 Lentiviral Activation Particles (h) - sc-412224-LAC from Santa Cruz Biotechnology
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TRMT6 Lentiviral Activation Particles (h2) - sc-412224-LAC-2 from Santa Cruz Biotechnology
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TRMT6 siRNA (h) - sc-76756 from Santa Cruz Biotechnology
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TRMT6 shRNA Plasmid (h) - sc-76756-SH from Santa Cruz Biotechnology
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TRMT6 shRNA (h) Lentiviral Particles - sc-76756-V from Santa Cruz Biotechnology
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CGI-09 RNAi - H00051605-R01 from Novus Biologicals
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MISSION® esiRNA - EHU087501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22041 from Sigma-Aldrich
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TRMT6 siRNA (Human) - CRH9856 from Cohesion Biosciences
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TRMT6 - MBS8230465 from MyBioSource
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shRNA set against Human TRMT6 (NM_015939.3) - SHH435344 from Creative biogene
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Human TRMT6 siRNA - orb270358 from Biorbyt
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TRMT6 shRNA Plasmid (Human) - CHH9856 from Cohesion Biosciences
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TRMT6 miRNA 3'UTR clone - MiUTR1H-02086 from Creative biogene
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