SIM2

Gene Symbol SIM2
Entrez Gene 6493
Alt Symbol HMC13F06, HMC29C01, SIM, bHLHe15
Species Human
Gene Type protein-coding
Description single-minded family bHLH transcription factor 2
Other Description class E basic helix-loop-helix protein 15|single-minded homolog 2|transcription factor SIM2
Swissprots Q2TBD8 Q16532 Q15470 Q15473 O60766 Q15471 Q15472 Q14190
Accessions BAA07906 BAA07907 BAA07908 BAA07909 BAA07910 BAA11108 BAA12919 BAA21489 BAA21490 BAA89433 EAX09737 EAX09738 Q14190 AI625864 AJ001858 CAA05055 AJ001859 BC052313 BC067104 BC110444 AAI10445 U80456 AAB62396 U80457 AAB62397 X83514 X83515 X84790 CAA59261 XM_011529694 XP_011527996 XM_011529695 XP_011527997 NM_005069 NP_005060 NM_009586 NP_033664
Function Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00632, ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:14697214}.

SIM2 L (C-17) - sc-8716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SIM2<sub>L</sub> (C-17): sc-8716. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts and Leydig cells.

SIM2 S (C-15) - sc-8715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SIM2<sub>S</sub> (C-15): sc-8715. Western blot analysis of SIM2<sub>S</sub> expression in FHs 173We whole cell lysate.

Anti-SIM2 antibody - ab94630 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SIM2 antibody (ab94630) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal kidney lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SIM2 antibody - ab55750 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55750 SIM2 antibody at 1ug/ml.

Anti-SIM2 antibody - ab110000 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-SIM2 antibody (ab110000) at 0.5 µg/ml + Fetal Mouse kidney lysate at 35 µg

Anti-SIM2 antibody [EPR7878] - ab131161 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7878
Anti-SIM2 antibody [EPR7878] (ab131161) at 1/1000 dilution + HepG2 cell lysate at 10 µgSecondaryHRP labelled goat anti-rabbit IgG at 1/2000 dilution

Anti-SIM2 Antibody (aa372-384) - LS-C10159 from LifeSpan Bioscience

Prices $265.00
Sizes 10 µg
Host Rabbit
Clonality Polyclonal

Anti-SIM2 Antibody (aa426-526) - LS-C126278 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SIM2 Antibody - LS-C332493 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SIM2 Antibody (aa428-437) - LS-C139715 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
SIM2 antibody (0.5 ug/ml) staining of fetal Mouse kidney lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SIM2 Antibody (N-Terminus) - LS-C110289 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SIM2 antibody LS-C110289 Western blot of Fetal Kidney lysate.

Anti-SIM2 Antibody (Internal, clone EPR7878) - LS-C154531 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7878
Western blot analysis on (A) fetal forebrain and (B) fetal brain lysate using anti-SIM2 antibody.

Anti-SIM2 Antibody (clone 3E6) - LS-C198198 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E6
Detection limit for recombinant GST tagged SIM2 is approximately 0.03 ng/ml as a capture antibody.

SIM2 Antibody - NBP1-88619 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SIM2 Antibody [NBP1-88619] - Staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear bodies.

SIM2 Antibody - NBP1-68864 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SIM2 Antibody [NBP1-68864] - (0.5ug/ml) staining of fetal Mouse kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SIM2 Antibody - H00006493-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SIM2 Antibody [H00006493-A01] - SIM2 polyclonal antibody (A01), Lot # O51024JC01 Western Blot analysis of SIM2 expression in HepG2 ( Cat # L019V1 ).

SIM2 Antibody (3E6) - H00006493-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E6
ELISA: SIM2 Antibody (3E6) [H00006493-M01] - Detection limit for recombinant GST tagged SIM2 is approximately 0.03ng/ml as a capture antibody.

SIM2 Polyclonal Antibody - bs-11951R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11951R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11951R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11951R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11951R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, Cy3 Conjugated - bs-11951R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, Cy5 Conjugated - bs-11951R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SIM2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11951R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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