Gene Symbol | Cct3 |
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Entrez Gene | 12462 |
Alt Symbol | AL024092, Cctg, Tcp1-rs3, TriC-P5 |
Species | Mouse |
Gene Type | protein-coding |
Description | chaperonin containing Tcp1, subunit 3 (gamma) |
Other Description | CCT-gamma|T-complex protein 1 subunit gamma|TCP-1-gamma|chaperonin subunit 3 (gamma)|matricin |
Swissprots | P80318 |
Accessions | BAA81873 EDL15307 P80318 AK031293 AK089548 AK146360 BAE27111 AK154043 BAE32334 AK156836 BAE33870 AK158223 AK158254 AK158272 AK161630 AK168052 AK171160 BAE42283 AK177771 AK179541 BC054776 BC139465 AAI39466 BC139467 AAI39468 L20509 AAA19749 Z31556 CAA83431 NM_009836 NP_033966 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. Plays a role in the assembly of the von Hippel-Lindau ubiquitination complex (By similarity). Interacts with DYX1C1. {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
TCP-1 γ CRISPR/Cas9 KO Plasmid (m) - sc-419524 from Santa Cruz Biotechnology
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TCP-1 γ HDR Plasmid (m) - sc-419524-HDR from Santa Cruz Biotechnology
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TCP-1 γ Double Nickase Plasmid (m) - sc-419524-NIC from Santa Cruz Biotechnology
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TCP-1 γ Double Nickase Plasmid (m2) - sc-419524-NIC-2 from Santa Cruz Biotechnology
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TCP-1 γ CRISPR Activation Plasmid (m) - sc-419524-ACT from Santa Cruz Biotechnology
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TCP-1 γ CRISPR Activation Plasmid (m2) - sc-419524-ACT-2 from Santa Cruz Biotechnology
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TCP-1 γ Lentiviral Activation Particles (m) - sc-419524-LAC from Santa Cruz Biotechnology
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TCP-1 γ Lentiviral Activation Particles (m2) - sc-419524-LAC-2 from Santa Cruz Biotechnology
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TCP-1 γ siRNA (m) - sc-36624 from Santa Cruz Biotechnology
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TCP-1 γ shRNA Plasmid (m) - sc-36624-SH from Santa Cruz Biotechnology
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TCP-1 γ shRNA (m) Lentiviral Particles - sc-36624-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN28294 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28294 from Sigma-Aldrich
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CCT3 siRNA (Mouse) - CRM0563 from Cohesion Biosciences
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CCT3 - MBS8230425 from MyBioSource
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shRNA set against Mouse CCT3 (NM_009836.1) - SHH258321 from Creative biogene
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shRNA set against Mouse Cct3(NM_009836.1) - SHG154198 from Creative biogene
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Mouse CCT3 siRNA - orb280039 from Biorbyt
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CCT3 shRNA Plasmid (Mouse) - CHM0563 from Cohesion Biosciences
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CCT3 miRNA 3'UTR clone - MiUTR1M-02721 from Creative biogene
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