Gene Symbol | SLC6A8 |
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Entrez Gene | 6535 |
Alt Symbol | CCDS1, CRT, CRTR, CT1, CTR5 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 8 |
Other Description | creatine transporter 1|creatine transporter SLC6A8 variant D|sodium- and chloride-dependent creatine transporter 1|solute carrier family 6 (neurotransmitter transporter, creatine), member 8|solute carrier family 6 member 8 |
Swissprots | Q66I36 B4DIA3 B2KY47 P48029 Q13032 E9PFC0 |
Accessions | AAA79507 AEO50955 CAA91442 EAW72827 EAW72830 EAW72832 P48029 AB209704 BAD92941 AK295495 BAG58415 AK309060 BC012355 AAH12355 BC081558 AAH81558 BE207407 CA424985 CX788315 DQ892306 ABM83232 DQ895505 ABM86431 EU280316 ABZ82022 KC800563 AHI18576 KJ534942 AHW56582 KJ534943 AHW56583 KJ534944 AHW56584 KJ534945 AHW56585 L31409 AAC41688 S74039 AAB32284 U17986 AAA86990 NM_001142805 NP_001136277 NM_001142806 NP_001136278 NM_005629 NP_005620 |
Function | Required for the uptake of creatine in muscles and brain. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate. {ECO:0000269|PubMed:7945388, ECO:0000269|PubMed:7953292}. |
SLC6A8 CRISPR/Cas9 KO Plasmid (h) - sc-404945 from Santa Cruz Biotechnology
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SLC6A8 HDR Plasmid (h) - sc-404945-HDR from Santa Cruz Biotechnology
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SLC6A8 Double Nickase Plasmid (h) - sc-404945-NIC from Santa Cruz Biotechnology
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SLC6A8 Double Nickase Plasmid (h2) - sc-404945-NIC-2 from Santa Cruz Biotechnology
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SLC6A8 CRISPR Activation Plasmid (h) - sc-404945-ACT from Santa Cruz Biotechnology
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SLC6A8 CRISPR Activation Plasmid (h2) - sc-404945-ACT-2 from Santa Cruz Biotechnology
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SLC6A8 Lentiviral Activation Particles (h) - sc-404945-LAC from Santa Cruz Biotechnology
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SLC6A8 Lentiviral Activation Particles (h2) - sc-404945-LAC-2 from Santa Cruz Biotechnology
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SLC6A8 siRNA (h) - sc-91252 from Santa Cruz Biotechnology
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SLC6A8 shRNA Plasmid (h) - sc-91252-SH from Santa Cruz Biotechnology
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SLC6A8 shRNA (h) Lentiviral Particles - sc-91252-V from Santa Cruz Biotechnology
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SLC6A8 RNAi - H00006535-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2303 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2303 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09495 from Sigma-Aldrich
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SLC6A8 siRNA (Human) - CRH4429 from Cohesion Biosciences
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SLC6A8 - MBS8224711 from MyBioSource
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SLC6A8 shRNA Plasmid (Human) - CHH4429 from Cohesion Biosciences
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SLC6A8 miRNA 3'UTR clone - MiUTR3H-02509 from Creative biogene
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SLC6A8 miRNA 3'UTR clone - MiUTR3H-02510 from Creative biogene
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SLC6A8 miRNA 3'UTR clone - MiUTR3H-02511 from Creative biogene
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