| Gene Symbol |
MUC17
|
| Entrez Gene |
140453
|
| Alt Symbol |
MUC3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mucin 17, cell surface associated
|
| Other Description |
MUC-17|MUC-3|membrane mucin MUC17|mucin-17|secreted mucin MUC17|small intestinal mucin MUC3|small intestinal mucin-3
|
| Swissprots |
Q685J3 O14761 Q8TDH7 Q685J2
|
| Accessions |
Q685J3 AF016692 AAB71685 AF016693 AAB71686 AF016694 AAB71687 AF430017 AAL89737 AJ606307 CAE54435 AJ606308 CAE54436 AK026404 BC126315 AAI26316 BM768498 BM773519 BM987743 XM_011515803 XP_011514105 XR_927365 NM_001040105 NP_001035194 NM_001004430
|
| Function |
Probably plays a role in maintaining homeostasis on mucosal surfaces. {ECO:0000269|PubMed:17990980}.
|
| Subcellular Location |
Isoform 1: Cell membrane; Single-pass membrane protein.
|
| Tissue Specificity |
Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers. {ECO:0000269|PubMed:11855812, ECO:0000269|PubMed:16737958, ECO:0000269|PubMed:9299468}.
|